Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9487
MIM: 605947
HGNC: 8966
Ensembl: ENSG00000108474
Variants:
dbSNP: 9487
ClinVar: 9487
TCGA: ENSG00000108474
COSMIC: PIGL
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37280393 | 2023 | Elevated nuclear PIGL disrupts the cMyc/BRD4 axis and improves PD-1 blockade therapy by dampening tumor immune evasion. | 3 |
| 37280393 | 2023 | Elevated nuclear PIGL disrupts the cMyc/BRD4 axis and improves PD-1 blockade therapy by dampening tumor immune evasion. | 3 |
| 28327575 | 2017 | Analysis of exome data for 4293 trios suggests GPI-anchor biogenesis defects are a rare cause of developmental disorders. | 41 |
| 28371479 | 2017 | Alu-mediated deletion of PIGL in a Patient with CHIME syndrome. | 7 |
| 28327575 | 2017 | Analysis of exome data for 4293 trios suggests GPI-anchor biogenesis defects are a rare cause of developmental disorders. | 41 |
| 28371479 | 2017 | Alu-mediated deletion of PIGL in a Patient with CHIME syndrome. | 7 |
| 25706356 | 2015 | Mutations in PIGL in a patient with Mabry syndrome. | 16 |
| 25706356 | 2015 | Mutations in PIGL in a patient with Mabry syndrome. | 16 |
| 22444671 | 2012 | Mutations in the glycosylphosphatidylinositol gene PIGL cause CHIME syndrome. | 59 |
| 22444671 | 2012 | Mutations in the glycosylphosphatidylinositol gene PIGL cause CHIME syndrome. | 59 |
Citation
Dessen P
PIGL (phosphatidylinositol glycan anchor biosynthesis class L)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41710/pigl-(phosphatidylinositol-glycan-anchor-biosynthesis-class-l)
