PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta)
2003-06-01 Affiliation
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5287
MIM: 602838
HGNC: 8972
Ensembl: ENSG00000133056
Variants:
dbSNP: 5287
ClinVar: 5287
TCGA: ENSG00000133056
COSMIC: PIK3C2B
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA134941638 | FGFR1OP | Gene | Pathway | associated | 20124951 | ||
| PA134972108 | FGFR1OP2 | Gene | Pathway | associated | 20124951 | ||
| PA24684 | AKT1 | Gene | Pathway | associated | 20124951, 28362716 | ||
| PA24685 | AKT2 | Gene | Pathway | associated | 20124951 | ||
| PA24686 | AKT3 | Gene | Pathway | associated | 20124951 | ||
| PA28127 | FGFR1 | Gene | Pathway | associated | 20124951 | ||
| PA28128 | FGFR2 | Gene | Pathway | associated | 20124951 | ||
| PA28129 | FGFR3 | Gene | Pathway | associated | 20124951 | ||
| PA28130 | FGFR4 | Gene | Pathway | associated | 20124951 | ||
| PA28131 | FGFR3P1 | Gene | Pathway | associated | 20124951 | ||
| PA28132 | FGFRL1 | Gene | Pathway | associated | 20124951 | ||
| PA28180 | FLT1 | Gene | Pathway | associated | 28362716 | ||
| PA28183 | FLT4 | Gene | Pathway | associated | 28362716 | ||
| PA29457 | HRH2 | Gene | Pathway | associated | |||
| PA30086 | KDR | Gene | Pathway | associated | 28362716 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35786744 | 2022 | Defective lipid signalling caused by mutations in PIK3C2B underlies focal epilepsy. | 6 |
| 35786744 | 2022 | Defective lipid signalling caused by mutations in PIK3C2B underlies focal epilepsy. | 6 |
| 33387369 | 2021 | The molecular mechanisms mediating class II PI 3-kinase function in cell physiology. | 6 |
| 33387369 | 2021 | The molecular mechanisms mediating class II PI 3-kinase function in cell physiology. | 6 |
| 32330555 | 2020 | Higher PIK3C2B gene expression of H1N1+ specific B-cells is associated with lower H1N1 immunogenicity after trivalent influenza vaccination in HIV infected children. | 5 |
| 32330555 | 2020 | Higher PIK3C2B gene expression of H1N1+ specific B-cells is associated with lower H1N1 immunogenicity after trivalent influenza vaccination in HIV infected children. | 5 |
| 30374841 | 2019 | The class II phosphoinositide 3-kinases PI3K-C2α and PI3K-C2β differentially regulate clathrin-dependent pinocytosis in human vascular endothelial cells. | 14 |
| 31752944 | 2019 | Downregulation of class II phosphoinositide 3-kinase PI3K-C2β delays cell division and potentiates the effect of docetaxel on cancer cell growth. | 10 |
| 30374841 | 2019 | The class II phosphoinositide 3-kinases PI3K-C2α and PI3K-C2β differentially regulate clathrin-dependent pinocytosis in human vascular endothelial cells. | 14 |
| 31752944 | 2019 | Downregulation of class II phosphoinositide 3-kinase PI3K-C2β delays cell division and potentiates the effect of docetaxel on cancer cell growth. | 10 |
| 29088297 | 2017 | Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis. | 3 |
| 29088297 | 2017 | Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis. | 3 |
| 25622909 | 2015 | Phosphatidylinositol 3-kinase, class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesis. | 17 |
| 25622909 | 2015 | Phosphatidylinositol 3-kinase, class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesis. | 17 |
| 23320105 | 2013 | Class II phosphoinositide 3-kinases contribute to endothelial cells morphogenesis. | 11 |
Citation
Dessen P
PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41712/pik3c2b-(phosphatidylinositol-4-phosphate-3-kinase-catalytic-subunit-type-2-beta)
