PLA2G2D (phospholipase A2 group IID)

2003-05-01  

Identity

HGNC
LOCATION
1p36.12
LOCUSID
ALIAS
PLA2IID,SPLASH,sPLA2-IID,sPLA2S
FUSION GENES

Other Information

Locus ID:

NCBI: 26279
MIM: 605630
HGNC: 9033
Ensembl: ENSG00000117215

Variants:

dbSNP: 26279
ClinVar: 26279
TCGA: ENSG00000117215
COSMIC: PLA2G2D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117215ENST00000375105Q9UNK4
ENSG00000117215ENST00000617227A0A087WZT4

Expression (GTEx)

0
1
2
3
4

Pathways

PathwaySourceExternal ID
Glycerophospholipid metabolismKEGGko00564
Ether lipid metabolismKEGGko00565
Arachidonic acid metabolismKEGGko00590
Linoleic acid metabolismKEGGko00591
alpha-Linolenic acid metabolismKEGGko00592
Glycerophospholipid metabolismKEGGhsa00564
Ether lipid metabolismKEGGhsa00565
Arachidonic acid metabolismKEGGhsa00590
Linoleic acid metabolismKEGGhsa00591
alpha-Linolenic acid metabolismKEGGhsa00592
Vascular smooth muscle contractionKEGGhsa04270
Vascular smooth muscle contractionKEGGko04270
Metabolic pathwaysKEGGhsa01100
Pancreatic secretionKEGGko04972
Pancreatic secretionKEGGhsa04972
Fat digestion and absorptionKEGGko04975
Fat digestion and absorptionKEGGhsa04975
Ras signaling pathwayKEGGhsa04014
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Synthesis of PAREACTOMER-HSA-1483166
Acyl chain remodelling of PEREACTOMER-HSA-1482839
Acyl chain remodelling of PCREACTOMER-HSA-1482788
Acyl chain remodelling of PSREACTOMER-HSA-1482801
Acyl chain remodelling of PIREACTOMER-HSA-1482922
Acyl chain remodelling of PGREACTOMER-HSA-1482925

References

Pubmed IDYearTitleCitations
150523242004Regulation of arachidonic acid availability for eicosanoid production.31
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
263922242015Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection.23
123967162002Increased gene expression of novel cytosolic and secretory phospholipase A(2) types in human airway epithelial cells induced by tumor necrosis factor-alpha and IFN-gamma.15
160025692005A novel polymorphism in secretory phospholipase A2-IID is associated with body weight loss in chronic obstructive pulmonary disease.11
160025692005A novel polymorphism in secretory phospholipase A2-IID is associated with body weight loss in chronic obstructive pulmonary disease.11
128952072003Allelic association study between phospholipase A2 genes and bipolar affective disorder.7
193651072009Gly80Ser polymorphism of phospholipase A2-IID is associated with cytokine inducibility in A549 cells.5
200561782010Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment.5
168973542005Interferon gamma-induced gene expression of the novel secretory phospholipase A2 type IID in human monocyte-derived macrophages is inhibited by lipopolysaccharide.4

Citation

Dessen P

PLA2G2D (phospholipase A2 group IID)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41731/pla2g2d-(phospholipase-a2-group-iid)