Identity
HGNC
LOCATION
1p36.22
LOCUSID
ALIAS
EDS6,EDSKCL1,LH,LH1,LLH,PLOD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5351
MIM: 153454
HGNC: 9081
Ensembl: ENSG00000083444
Variants:
dbSNP: 5351
ClinVar: 5351
TCGA: ENSG00000083444
COSMIC: PLOD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000083444 | ENST00000196061 | Q02809 |
| ENSG00000083444 | ENST00000196061 | A0A024R4H0 |
| ENSG00000083444 | ENST00000429000 | Q5JXB7 |
| ENSG00000083444 | ENST00000449038 | Q5JXB8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36695693 | 2023 | miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages. | 1 |
| 36695693 | 2023 | miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages. | 1 |
| 34400365 | 2022 | New mechanistic insights to PLOD1-mediated human vascular disease. | 10 |
| 34845571 | 2022 | PLOD1 acts as a tumor promoter in glioma via activation of the HSF1 signaling pathway. | 4 |
| 35149972 | 2022 | P3H4 and PLOD1 expression associates with poor prognosis in bladder cancer. | 3 |
| 34400365 | 2022 | New mechanistic insights to PLOD1-mediated human vascular disease. | 10 |
| 34845571 | 2022 | PLOD1 acts as a tumor promoter in glioma via activation of the HSF1 signaling pathway. | 4 |
| 35149972 | 2022 | P3H4 and PLOD1 expression associates with poor prognosis in bladder cancer. | 3 |
| 33420370 | 2021 | Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling. | 23 |
| 33483598 | 2021 | PLODs are overexpressed in ovarian cancer and are associated with gap junctions via connexin 43. | 8 |
| 33579342 | 2021 | A floppy infant without lingual frenulum and kyphoscoliosis: Ehlers Danlos syndrome case report. | 2 |
| 34304093 | 2021 | Characterization of a cancer-associated Epstein-Barr virus EBNA1 variant reveals a novel interaction with PLOD1 and PLOD3. | 4 |
| 34455762 | 2021 | PLOD1 promotes cell growth and aerobic glycolysis by regulating the SOX9/PI3K/Akt/mTOR signaling pathway in gastric cancer. | 8 |
| 33420370 | 2021 | Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling. | 23 |
| 33483598 | 2021 | PLODs are overexpressed in ovarian cancer and are associated with gap junctions via connexin 43. | 8 |
Citation
Dessen P
PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41749/plod1-(procollagen-lysine-2-oxoglutarate-5-dioxygenase-1)
