PLXDC2 (plexin domain containing 2)

2003-06-01  

Identity

HGNC
PLXDC2
LOCATION
10p12.31
LOCUSID
84898
ALIAS
TEM7R
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84898
MIM: 606827
HGNC: 21013
Ensembl: ENSG00000120594

Variants:

dbSNP: 84898
ClinVar: 84898
TCGA: ENSG00000120594
COSMIC: PLXDC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000120594ENST00000377242Q6UX71
ENSG00000120594ENST00000377252Q6UX71

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
heart muscle
smooth muscle
skeletal muscle
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
370898642023Adaptive c-Met-PLXDC2 Signaling Axis Mediates Cancer Stem Cell Plasticity to Confer Radioresistance-associated Aggressiveness in Head and Neck Cancer.3
370898642023Adaptive c-Met-PLXDC2 Signaling Axis Mediates Cancer Stem Cell Plasticity to Confer Radioresistance-associated Aggressiveness in Head and Neck Cancer.3
336571662021Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV).5
341462552021Plexin domain containing protein 2 is more expressed within the invasive area of human colorectal cancer tissues.0
347776332021The Upregulation of PLXDC2 Correlates with Immune Microenvironment Characteristics and Predicts Prognosis in Gastric Cancer.4
336571662021Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV).5
341462552021Plexin domain containing protein 2 is more expressed within the invasive area of human colorectal cancer tissues.0
347776332021The Upregulation of PLXDC2 Correlates with Immune Microenvironment Characteristics and Predicts Prognosis in Gastric Cancer.4
322029492020Expression Pattern of Plexin Domain Containing 2 in Human Hepatocellular Carcinoma.5
322029492020Expression Pattern of Plexin Domain Containing 2 in Human Hepatocellular Carcinoma.5
312717012019A Genome Wide Association Study on plasma FV levels identified PLXDC2 as a new modifier of the coagulation process.2
312717012019A Genome Wide Association Study on plasma FV levels identified PLXDC2 as a new modifier of the coagulation process.2
303269572018Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort.4
303269572018Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort.4
289308872017Genetic Variant Near PLXDC2 Influences the Risk of Primary Open-angle Glaucoma by Increasing Intraocular Pressure in the Japanese Population.4

Citation

Dessen P

PLXDC2 (plexin domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41753/plxdc2-(plexin-domain-containing-2)