Identity
HGNC
LOCATION
14q21.1
LOCUSID
ALIAS
DRS,DRSP,SDK3,memA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5411
MIM: 603154
HGNC: 9162
Ensembl: ENSG00000100941
Variants:
dbSNP: 5411
ClinVar: 5411
TCGA: ENSG00000100941
COSMIC: PNN
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000100941 | ENST00000216832 | Q9H307 |
| ENSG00000100941 | ENST00000553331 | G3V579 |
| ENSG00000100941 | ENST00000556530 | G3V5F0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38892168 | 2024 | Identification of a Novel miR-195-5p/PNN Axis in Colorectal Cancer. | 0 |
| 38892168 | 2024 | Identification of a Novel miR-195-5p/PNN Axis in Colorectal Cancer. | 0 |
| 35257416 | 2022 | The prognostic effect of PNN in digestive tract cancers and its correlation with the tumor immune landscape in colon adenocarcinoma. | 4 |
| 35996844 | 2022 | Methyltransferase like 3 enhances pinin mRNA stability through N(6) -methyladenosine modification to augment tumourigenesis of colon adenocarcinoma. | 2 |
| 35257416 | 2022 | The prognostic effect of PNN in digestive tract cancers and its correlation with the tumor immune landscape in colon adenocarcinoma. | 4 |
| 35996844 | 2022 | Methyltransferase like 3 enhances pinin mRNA stability through N(6) -methyladenosine modification to augment tumourigenesis of colon adenocarcinoma. | 2 |
| 33786605 | 2021 | Hsa_circ_0032463 acts as the tumor promoter in osteosarcoma by regulating the miR‑330‑3p/PNN axis. | 8 |
| 33811436 | 2021 | Pinin acts as a poor prognostic indicator for renal cell carcinoma by reducing apoptosis and promoting cell migration and invasion. | 9 |
| 33786605 | 2021 | Hsa_circ_0032463 acts as the tumor promoter in osteosarcoma by regulating the miR‑330‑3p/PNN axis. | 8 |
| 33811436 | 2021 | Pinin acts as a poor prognostic indicator for renal cell carcinoma by reducing apoptosis and promoting cell migration and invasion. | 9 |
| 32203416 | 2020 | piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis. | 29 |
| 32203416 | 2020 | piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis. | 29 |
| 30973654 | 2019 | RNA sequencing reveals PNN and KCNQ1OT1 as predictive biomarkers of clinical outcome in stage III colorectal cancer patients treated with adjuvant chemotherapy. | 20 |
| 30973654 | 2019 | RNA sequencing reveals PNN and KCNQ1OT1 as predictive biomarkers of clinical outcome in stage III colorectal cancer patients treated with adjuvant chemotherapy. | 20 |
| 28595116 | 2017 | The unique spliceosome signature of human pluripotent stem cells is mediated by SNRPA1, SNRPD1, and PNN. | 20 |
Citation
Dessen P
PNN (pinin, desmosome associated protein)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41767/pnn-(pinin-desmosome-associated-protein)
