Identity
HGNC
LOCATION
11q13.4
LOCUSID
ALIAS
P66,P68,PPP1R128
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10714
MIM: 611415
HGNC: 20932
Ensembl: ENSG00000077514
Variants:
dbSNP: 10714
ClinVar: 10714
TCGA: ENSG00000077514
COSMIC: POLD3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36718939 | 2023 | Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing. | 3 |
| 37030525 | 2023 | POLD3 deficiency is associated with severe combined immunodeficiency, neurodevelopmental delay, and hearing impairment. | 1 |
| 36718939 | 2023 | Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing. | 3 |
| 37030525 | 2023 | POLD3 deficiency is associated with severe combined immunodeficiency, neurodevelopmental delay, and hearing impairment. | 1 |
| 35786622 | 2022 | Interaction of CCND2, CDKN1A, and POLD3 Variants in Mexican Patients with Colorectal Cancer. | 0 |
| 35786622 | 2022 | Interaction of CCND2, CDKN1A, and POLD3 Variants in Mexican Patients with Colorectal Cancer. | 0 |
| 31777915 | 2020 | An R-loop-initiated CSB-RAD52-POLD3 pathway suppresses ROS-induced telomeric DNA breaks. | 48 |
| 33077594 | 2020 | Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair. | 12 |
| 31777915 | 2020 | An R-loop-initiated CSB-RAD52-POLD3 pathway suppresses ROS-induced telomeric DNA breaks. | 48 |
| 33077594 | 2020 | Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair. | 12 |
| 28934474 | 2017 | Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro. | 4 |
| 28934474 | 2017 | Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro. | 4 |
| 26916162 | 2016 | Multiple Forms of Human DNA Polymerase Delta Sub-Assembling in Cellular DNA Transactions. | 3 |
| 26982350 | 2016 | Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis. | 38 |
| 27185888 | 2016 | In vivo evidence for translesion synthesis by the replicative DNA polymerase δ. | 27 |
Citation
Dessen P
POLD3 (DNA polymerase delta 3, accessory subunit)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/41771/pold3-(dna-polymerase-delta-3-accessory-subunit)
