PPFIBP1 (PPFIA binding protein 1)

2003-10-01  

Identity

HGNC
PPFIBP1
LOCATION
12p11.23
LOCUSID
8496
ALIAS
L2,SGT2,hSGT2,hSgt2p
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8496
MIM: 603141
HGNC: 9249
Ensembl: ENSG00000110841

Variants:

dbSNP: 8496
ClinVar: 8496
TCGA: ENSG00000110841
COSMIC: PPFIBP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000110841ENST00000228425Q86W92
ENSG00000110841ENST00000318304Q86W92
ENSG00000110841ENST00000535047Q86W92
ENSG00000110841ENST00000535575F5H6Q7
ENSG00000110841ENST00000537261H0YGH8
ENSG00000110841ENST00000537927Q86W92
ENSG00000110841ENST00000537927A0A024RB02
ENSG00000110841ENST00000538433F5H7K5
ENSG00000110841ENST00000539326H0YFE4
ENSG00000110841ENST00000540114F5GZP6
ENSG00000110841ENST00000542187F5H495
ENSG00000110841ENST00000542629Q86W92
ENSG00000110841ENST00000545334F5H0E0
ENSG00000110841ENST00000545381A0A0A0MTP2
ENSG00000110841ENST00000619325A0A087WVX8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
118362602002Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1).42
218557982011Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures.25
214300682011Pulmonary inflammatory myofibroblastic tumor expressing a novel fusion, PPFIBP1-ALK: reappraisal of anti-ALK immunohistochemistry as a tool for novel ALK fusion identification.21
199656222010Liprin (beta)1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity.17
266633472016Effects of the scaffold proteins liprin-α1, β1 and β2 on invasion by breast cancer cells.8
267393302016Association of liprin β-1 with kank proteins in melanoma.4

Citation

Dessen P

PPFIBP1 (PPFIA binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-10-01

Online version: http://atlasgeneticsoncology.org/gene/41798/ppfibp1-(ppfia-binding-protein-1)