PPIL2 (peptidylprolyl isomerase like 2)

2003-05-01  

Identity

HGNC
PPIL2
LOCATION
22q11.21
LOCUSID
23759
ALIAS
CYC4,CYP60,Cyp-60,UBOX7,hCyP-60
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23759
MIM: 607588
HGNC: 9261
Ensembl: ENSG00000100023

Variants:

dbSNP: 23759
ClinVar: 23759
TCGA: ENSG00000100023
COSMIC: PPIL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100023ENST00000335025Q13356
ENSG00000100023ENST00000335025A0A024R1C1
ENSG00000100023ENST00000398831Q13356
ENSG00000100023ENST00000398831A0A024R1C1
ENSG00000100023ENST00000406385Q13356
ENSG00000100023ENST00000406385A0A024R1C1
ENSG00000100023ENST00000417788F8WC56
ENSG00000100023ENST00000458567C9JDF0
ENSG00000100023ENST00000626352Q13356

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Ubiquitin mediated proteolysisKEGGko04120
Ubiquitin mediated proteolysisKEGGhsa04120
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733
Basigin interactionsREACTOMER-HSA-210991

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
196696072009Variation in RTN3 and PPIL2 genes does not influence platelet membrane beta-secretase activity or susceptibility to alzheimer's disease in the northern Irish population.1
196696072009Variation in RTN3 and PPIL2 genes does not influence platelet membrane beta-secretase activity or susceptibility to alzheimer's disease in the northern Irish population.1
196696072009Variation in RTN3 and PPIL2 genes does not influence platelet membrane beta-secretase activity or susceptibility to alzheimer's disease in the northern Irish population.1
196696072009Variation in RTN3 and PPIL2 genes does not influence platelet membrane beta-secretase activity or susceptibility to alzheimer's disease in the northern Irish population.1
159469522005Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60.32
159469522005Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60.32

Citation

Dessen P

PPIL2 (peptidylprolyl isomerase like 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41800/ppil2-(peptidylprolyl-isomerase-like-2)