Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23645
MIM: 611048
HGNC: 14375
Ensembl: ENSG00000087074
Variants:
dbSNP: 23645
ClinVar: 23645
TCGA: ENSG00000087074
COSMIC: PPP1R15A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000087074 | ENST00000200453 | O75807 |
| ENSG00000087074 | ENST00000600406 | M0QXL1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38365764 | 2024 | Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers. | 0 |
| 38602876 | 2024 | Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress. | 0 |
| 38365764 | 2024 | Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers. | 0 |
| 38602876 | 2024 | Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress. | 0 |
| 38139150 | 2023 | The PPP1R15 Family of eIF2-alpha Phosphatase Targeting Subunits (GADD34 and CReP). | 3 |
| 38139150 | 2023 | The PPP1R15 Family of eIF2-alpha Phosphatase Targeting Subunits (GADD34 and CReP). | 3 |
| 34985336 | 2022 | Enterovirus 71 Activates GADD34 via Precursor 3CD to Promote IRES-Mediated Viral Translation. | 3 |
| 34985336 | 2022 | Enterovirus 71 Activates GADD34 via Precursor 3CD to Promote IRES-Mediated Viral Translation. | 3 |
| 34625748 | 2021 | Higher-order phosphatase-substrate contacts terminate the integrated stress response. | 10 |
| 34732748 | 2021 | Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF. | 7 |
| 34847777 | 2021 | Substrate recognition determinants of human eIF2α phosphatases. | 3 |
| 34625748 | 2021 | Higher-order phosphatase-substrate contacts terminate the integrated stress response. | 10 |
| 34732748 | 2021 | Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF. | 7 |
| 34847777 | 2021 | Substrate recognition determinants of human eIF2α phosphatases. | 3 |
| 32978159 | 2020 | GADD34 is a modulator of autophagy during starvation. | 29 |
Citation
Dessen P
PPP1R15A (protein phosphatase 1 regulatory subunit 15A)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41808/
