PPP1R9A (protein phosphatase 1 regulatory subunit 9A)

2003-12-01  

Identity

HGNC
PPP1R9A
LOCATION
7q21.3
LOCUSID
55607
ALIAS
NRB1,NRBI,Neurabin-I
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55607
MIM: 602468
HGNC: 14946
Ensembl: ENSG00000158528

Variants:

dbSNP: 55607
ClinVar: 55607
TCGA: ENSG00000158528
COSMIC: PPP1R9A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158528ENST00000289495Q9ULJ8
ENSG00000158528ENST00000340694Q9ULJ8
ENSG00000158528ENST00000413325C9J730
ENSG00000158528ENST00000422324C9J3G5
ENSG00000158528ENST00000424654Q9ULJ8
ENSG00000158528ENST00000433360Q9ULJ8
ENSG00000158528ENST00000433881Q9ULJ8
ENSG00000158528ENST00000456331Q9ULJ8

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
222845382013Structural basis for protein phosphatase 1 regulation and specificity.74
152861552004Genomic imprinting of PPP1R9A encoding neurabin I in skeletal muscle and extra-embryonic tissues.16
204234812010Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study.13
250578522014Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma.12
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
257577152015Altered prefrontal cortical MARCKS and PPP1R9A mRNA expression in schizophrenia and bipolar disorder.7
302497862018Hyper-N-glycosylated SAMD14 and neurabin-I as driver autoantigens of primary central nervous system lymphoma.2

Citation

Dessen P

PPP1R9A (protein phosphatase 1 regulatory subunit 9A)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41812/ppp1r9a-(protein-phosphatase-1-regulatory-subunit-9a)