Identity
HGNC
LOCATION
8p21.2
LOCUSID
ALIAS
B55A,B55ALPHA,PR52A,PR55A,PR55alpha
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5520
MIM: 604941
HGNC: 9304
Ensembl: ENSG00000221914
Variants:
dbSNP: 5520
ClinVar: 5520
TCGA: ENSG00000221914
COSMIC: PPP2R2A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38441530 | 2024 | PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation. | 0 |
| 38441530 | 2024 | PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation. | 0 |
| 37543698 | 2023 | PP2A-B55alpha controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus. | 2 |
| 37543698 | 2023 | PP2A-B55alpha controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus. | 2 |
| 32950569 | 2021 | AMOTL2 inhibits JUN Thr239 dephosphorylation by binding PPP2R2A to suppress the proliferation in non-small cell lung cancer cells. | 10 |
| 33798913 | 2021 | LncRNA-HCG18 regulates the viability, apoptosis, migration, invasion and epithelial-mesenchymal transition of papillary thyroid cancer cells via regulating the miR-106a-5p/PPP2R2A axis. | 11 |
| 34661528 | 2021 | PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107. | 16 |
| 32950569 | 2021 | AMOTL2 inhibits JUN Thr239 dephosphorylation by binding PPP2R2A to suppress the proliferation in non-small cell lung cancer cells. | 10 |
| 33798913 | 2021 | LncRNA-HCG18 regulates the viability, apoptosis, migration, invasion and epithelial-mesenchymal transition of papillary thyroid cancer cells via regulating the miR-106a-5p/PPP2R2A axis. | 11 |
| 34661528 | 2021 | PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107. | 16 |
| 31875526 | 2020 | Long noncoding RNA GMAN promotes hepatocellular carcinoma progression by interacting with eIF4B. | 26 |
| 31901078 | 2020 | 14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation. | 14 |
| 31923339 | 2020 | microRNA-665 is down-regulated in gastric cancer and inhibits proliferation, invasion, and EMT by targeting PPP2R2A. | 18 |
| 32527198 | 2020 | B55α/PP2A Limits Endothelial Cell Apoptosis During Vascular Remodeling: A Complementary Approach To Disrupt Pathological Vessels? | 15 |
| 31875526 | 2020 | Long noncoding RNA GMAN promotes hepatocellular carcinoma progression by interacting with eIF4B. | 26 |
Citation
Dessen P
PPP2R2A (protein phosphatase 2 regulatory subunit Balpha)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41815/ppp2r2a-(protein-phosphatase-2-regulatory-subunit-balpha)
