Identity
HGNC
LOCATION
3q22.3
LOCUSID
ALIAS
PPP2R3,PR130,PR72
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5523
MIM: 604944
HGNC: 9307
Ensembl: ENSG00000073711
Variants:
dbSNP: 5523
ClinVar: 5523
TCGA: ENSG00000073711
COSMIC: PPP2R3A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000073711 | ENST00000264977 | Q06190 |
| ENSG00000073711 | ENST00000334546 | Q06190 |
| ENSG00000073711 | ENST00000447251 | H7C1M1 |
| ENSG00000073711 | ENST00000490467 | Q06190 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35945177 | 2022 | Overexpression of Protein Phosphatase 2 Regulatory Subunit B"Alpha Promotes Glycolysis by Regulating Hexokinase 1 in Hepatocellular Carcinoma. | 3 |
| 35945177 | 2022 | Overexpression of Protein Phosphatase 2 Regulatory Subunit B"Alpha Promotes Glycolysis by Regulating Hexokinase 1 in Hepatocellular Carcinoma. | 3 |
| 34262014 | 2021 | A novel dephosphorylation targeting chimera selectively promoting tau removal in tauopathies. | 14 |
| 34262014 | 2021 | A novel dephosphorylation targeting chimera selectively promoting tau removal in tauopathies. | 14 |
| 32392189 | 2020 | [Functional Hypermethylation of ALDH1L1, PLCL2, and PPP2R3A in Colon Cancer]. | 3 |
| 33068647 | 2020 | The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformation. | 12 |
| 32392189 | 2020 | [Functional Hypermethylation of ALDH1L1, PLCL2, and PPP2R3A in Colon Cancer]. | 3 |
| 33068647 | 2020 | The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformation. | 12 |
| 29472538 | 2018 | HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130. | 30 |
| 29472538 | 2018 | HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130. | 30 |
| 26945059 | 2016 | PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration. | 15 |
| 26945059 | 2016 | PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration. | 15 |
| 18397887 | 2008 | Protein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunit. | 22 |
| 18397887 | 2008 | Protein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunit. | 22 |
| 17535922 | 2007 | The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A. | 56 |
Citation
Dessen P
PPP2R3A (protein phosphatase 2 regulatory subunit Balpha)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41816/ppp2r3a-(protein-phosphatase-2-regulatory-subunit-balpha)
