Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5557
MIM: 176635
HGNC: 9369
Ensembl: ENSG00000198056
Variants:
dbSNP: 5557
ClinVar: 5557
TCGA: ENSG00000198056
COSMIC: PRIM1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198056 | ENST00000338193 | P49642 |
| ENSG00000198056 | ENST00000549549 | H0YIP2 |
| ENSG00000198056 | ENST00000550770 | F8VNY2 |
| ENSG00000198056 | ENST00000552590 | F8VSB2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38773012 | 2024 | Variable Syndromic Immunodeficiency in Patients with Biallelic PRIM1 Mutations. | 0 |
| 38773012 | 2024 | Variable Syndromic Immunodeficiency in Patients with Biallelic PRIM1 Mutations. | 0 |
| 34376693 | 2021 | Small tandem DNA duplications result from CST-guided Pol α-primase action at DNA break termini. | 18 |
| 34376693 | 2021 | Small tandem DNA duplications result from CST-guided Pol α-primase action at DNA break termini. | 18 |
| 32908930 | 2020 | DNA Primase Subunit 1 Expression in Hepatocellular Carcinoma and Its Clinical Implication. | 1 |
| 32908930 | 2020 | DNA Primase Subunit 1 Expression in Hepatocellular Carcinoma and Its Clinical Implication. | 1 |
| 30097999 | 2019 | DNA primase polypeptide 1 (PRIM1) involves in estrogen-induced breast cancer formation through activation of the G2/M cell cycle checkpoint. | 15 |
| 30097999 | 2019 | DNA primase polypeptide 1 (PRIM1) involves in estrogen-induced breast cancer formation through activation of the G2/M cell cycle checkpoint. | 15 |
| 30257222 | 2018 | Inactivation of PRIM1 Function Sensitizes Cancer Cells to ATR and CHK1 Inhibitors. | 13 |
| 30446220 | 2018 | Structural and biochemical insights into inhibition of human primase by citrate. | 2 |
| 30257222 | 2018 | Inactivation of PRIM1 Function Sensitizes Cancer Cells to ATR and CHK1 Inhibitors. | 13 |
| 30446220 | 2018 | Structural and biochemical insights into inhibition of human primase by citrate. | 2 |
| 26710848 | 2016 | Insight into the Human DNA Primase Interaction with Template-Primer. | 41 |
| 27599756 | 2016 | Variation analysis of PRIM1 gene in Chinese patients with primary ovarian insufficiency. | 3 |
| 26710848 | 2016 | Insight into the Human DNA Primase Interaction with Template-Primer. | 41 |
Citation
Dessen P
PRIM1 (DNA primase subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41844/prim1-(dna-primase-subunit-1)
