Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5567
MIM: 176892
HGNC: 9381
Ensembl: ENSG00000142875
Variants:
dbSNP: 5567
ClinVar: 5567
TCGA: ENSG00000142875
COSMIC: PRKACB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA26008 | CACNA1B | Gene | Pathway | associated | |||
| PA30616 | MAPK1 | Gene | Pathway | associated | |||
| PA59 | ARRB1 | Gene | Pathway | associated | |||
| PA60 | ARRB2 | Gene | Pathway | associated | |||
| PA83 | CACNA1C | Gene | Pathway | associated | |||
| PA84 | CACNA1D | Gene | Pathway | associated | |||
| PA85 | CACNA1S | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37871652 | 2024 | Gene Rearrangement and Expression of PRKACA and PRKACB Govern Morphobiology of Pancreatobiliary Oncocytic Neoplasms. | 1 |
| 37871652 | 2024 | Gene Rearrangement and Expression of PRKACA and PRKACB Govern Morphobiology of Pancreatobiliary Oncocytic Neoplasms. | 1 |
| 34787019 | 2022 | Expressing MLH1 in HCT116 cells increases cellular resistance to radiation by activating the PRKAC. | 2 |
| 36152045 | 2022 | Investigation of -PRKACA/-PRKACB fusion genes in oncocytic tumors of the pancreatobiliary and other systems. | 1 |
| 34787019 | 2022 | Expressing MLH1 in HCT116 cells increases cellular resistance to radiation by activating the PRKAC. | 2 |
| 36152045 | 2022 | Investigation of -PRKACA/-PRKACB fusion genes in oncocytic tumors of the pancreatobiliary and other systems. | 1 |
| 34244791 | 2021 | The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF. | 2 |
| 34667254 | 2021 | Novel implications of a strictly monomorphic (GCC) repeat in the human PRKACB gene. | 2 |
| 34244791 | 2021 | The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF. | 2 |
| 34667254 | 2021 | Novel implications of a strictly monomorphic (GCC) repeat in the human PRKACB gene. | 2 |
| 31678302 | 2020 | Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct. | 50 |
| 31998791 | 2020 | MicroRNA-384 Inhibits the Progression of Papillary Thyroid Cancer by Targeting PRKACB. | 8 |
| 33055300 | 2020 | PRKACB variants in skeletal disease or adrenocortical hyperplasia: effects on protein kinase A. | 2 |
| 33058759 | 2020 | Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome. | 19 |
| 31678302 | 2020 | Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct. | 50 |
Citation
Dessen P
PRKACB (protein kinase cAMP-activated catalytic subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41847/prkacb-(protein-kinase-camp-activated-catalytic-subunit-beta)
