Identity
HGNC
LOCATION
20q13.12
LOCUSID
ALIAS
PRKCBP1,PRO2893,RACK7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23613
MIM: 615713
HGNC: 9397
Ensembl: ENSG00000101040
Variants:
dbSNP: 23613
ClinVar: 23613
TCGA: ENSG00000101040
COSMIC: ZMYND8
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35916866 | 2022 | De Novo ZMYND8 variants result in an autosomal dominant neurodevelopmental disorder with cardiac malformations. | 1 |
| 35916866 | 2022 | De Novo ZMYND8 variants result in an autosomal dominant neurodevelopmental disorder with cardiac malformations. | 1 |
| 33148660 | 2021 | ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth. | 9 |
| 33593912 | 2021 | ZMYND8 preferentially binds phosphorylated EZH2 to promote a PRC2-dependent to -independent function switch in hypoxia-inducible factor-activated cancer. | 11 |
| 34358447 | 2021 | ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency. | 19 |
| 34462784 | 2021 | Validation of ZMYND8 as a new treatment target in hepatocellular carcinoma. | 2 |
| 33148660 | 2021 | ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth. | 9 |
| 33593912 | 2021 | ZMYND8 preferentially binds phosphorylated EZH2 to promote a PRC2-dependent to -independent function switch in hypoxia-inducible factor-activated cancer. | 11 |
| 34358447 | 2021 | ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency. | 19 |
| 34462784 | 2021 | Validation of ZMYND8 as a new treatment target in hepatocellular carcinoma. | 2 |
| 31965980 | 2020 | A novel role of tumor suppressor ZMYND8 in inducing differentiation of breast cancer cells through its dual-histone binding function. | 3 |
| 32224527 | 2020 | ZMYND8 expression combined with pN and pM classification as a novel prognostic prediction model for colorectal cancer: Based on TCGA and GEO database analysis. | 7 |
| 32832624 | 2020 | RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma. | 16 |
| 33323928 | 2020 | Suppression of poised oncogenes by ZMYND8 promotes chemo-sensitization. | 9 |
| 31965980 | 2020 | A novel role of tumor suppressor ZMYND8 in inducing differentiation of breast cancer cells through its dual-histone binding function. | 3 |
Citation
Dessen P
ZMYND8 (zinc finger MYND-type containing 8)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41853/zmynd8-(zinc-finger-mynd-type-containing-8)
