Identity
HGNC
LOCATION
19p13.12
LOCUSID
ALIAS
DBK,PAK-1,PAK1,PKN,PKN-ALPHA,PRK1,PRKCL1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5585
MIM: 601032
HGNC: 9405
Ensembl: ENSG00000123143
Variants:
dbSNP: 5585
ClinVar: 5585
TCGA: ENSG00000123143
COSMIC: PKN1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35533253 | 2022 | Upregulation of PKN1 as a Prognosis Biomarker for Endometrial Cancer. | 0 |
| 35533253 | 2022 | Upregulation of PKN1 as a Prognosis Biomarker for Endometrial Cancer. | 0 |
| 31981797 | 2020 | Cyclin-dependent kinase 1-mediated phosphorylation of protein kinase N1 promotes anchorage-independent growth and migration. | 5 |
| 32127582 | 2020 | Novel roles of PRK1 and PRK2 in cilia and cancer biology. | 5 |
| 31981797 | 2020 | Cyclin-dependent kinase 1-mediated phosphorylation of protein kinase N1 promotes anchorage-independent growth and migration. | 5 |
| 32127582 | 2020 | Novel roles of PRK1 and PRK2 in cilia and cancer biology. | 5 |
| 30742064 | 2019 | Protein Kinase N1 control of androgen-responsive serum response factor action provides rationale for novel prostate cancer treatment strategy. | 6 |
| 31045890 | 2019 | Secretory Carcinoma of the Skin: Report of 6 Cases, Including a Case With a Novel NFIX-PKN1 Translocation. | 9 |
| 31125460 | 2019 | Characterization of the novel cardiolipin binding regions identified on the protease and lipid activated PKC-related kinase 1. | 3 |
| 30742064 | 2019 | Protein Kinase N1 control of androgen-responsive serum response factor action provides rationale for novel prostate cancer treatment strategy. | 6 |
| 31045890 | 2019 | Secretory Carcinoma of the Skin: Report of 6 Cases, Including a Case With a Novel NFIX-PKN1 Translocation. | 9 |
| 31125460 | 2019 | Characterization of the novel cardiolipin binding regions identified on the protease and lipid activated PKC-related kinase 1. | 3 |
| 28222172 | 2017 | RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling. | 10 |
| 28875501 | 2017 | The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression. | 19 |
| 28222172 | 2017 | RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling. | 10 |
Citation
Dessen P
PKN1 (protein kinase N1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41858/pkn1-(protein-kinase-n1)
