Identity
HGNC
LOCATION
1p22.2
LOCUSID
ALIAS
PAK2,PRK2,PRKCL2,PRO2042,Pak-2,STK7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5586
MIM: 602549
HGNC: 9406
Ensembl: ENSG00000065243
Variants:
dbSNP: 5586
ClinVar: 5586
TCGA: ENSG00000065243
COSMIC: PKN2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38505918 | 2024 | Increased PKN2 and M2-Polarized Macrophages Promote HCT116 Cell Invasion. | 0 |
| 38505918 | 2024 | Increased PKN2 and M2-Polarized Macrophages Promote HCT116 Cell Invasion. | 0 |
| 35895078 | 2022 | Genome-Wide Association Study for Idiopathic Ventricular Tachyarrhythmias Identifies Key Role of CCR7 and PKN2 in Calcium Homeostasis and Cardiac Rhythm Maintenance. | 2 |
| 35895078 | 2022 | Genome-Wide Association Study for Idiopathic Ventricular Tachyarrhythmias Identifies Key Role of CCR7 and PKN2 in Calcium Homeostasis and Cardiac Rhythm Maintenance. | 2 |
| 33879018 | 2021 | LINC00668 cooperated with HuR dependent upregulation of PKN2 to facilitate gastric cancer metastasis. | 4 |
| 34499618 | 2021 | Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation. | 17 |
| 34759927 | 2021 | Role of PKM2-Mediated Immunometabolic Reprogramming on Development of Cytokine Storm. | 15 |
| 33879018 | 2021 | LINC00668 cooperated with HuR dependent upregulation of PKN2 to facilitate gastric cancer metastasis. | 4 |
| 34499618 | 2021 | Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation. | 17 |
| 34759927 | 2021 | Role of PKM2-Mediated Immunometabolic Reprogramming on Development of Cytokine Storm. | 15 |
| 32127582 | 2020 | Novel roles of PRK1 and PRK2 in cilia and cancer biology. | 5 |
| 32127582 | 2020 | Novel roles of PRK1 and PRK2 in cilia and cancer biology. | 5 |
| 29368606 | 2018 | PKN2 in colon cancer cells inhibits M2 phenotype polarization of tumor-associated macrophages via regulating DUSP6-Erk1/2 pathway. | 63 |
| 29368606 | 2018 | PKN2 in colon cancer cells inhibits M2 phenotype polarization of tumor-associated macrophages via regulating DUSP6-Erk1/2 pathway. | 63 |
| 28720584 | 2017 | Protein kinase N2 regulates AMP kinase signaling and insulin responsiveness of glucose metabolism in skeletal muscle. | 10 |
Citation
Dessen P
PKN2 (protein kinase N2)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41859/
