Identity
HGNC
LOCATION
4q21.21
LOCUSID
ALIAS
PKG2,PRKGR2,cGK2,cGKII
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5593
MIM: 601591
HGNC: 9416
Ensembl: ENSG00000138669
Variants:
dbSNP: 5593
ClinVar: 5593
TCGA: ENSG00000138669
COSMIC: PRKG2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36504352 | 2023 | Natural history of clinical features in two brothers with acromesomelic dysplasia related to PRKG2. | 0 |
| 36504352 | 2023 | Natural history of clinical features in two brothers with acromesomelic dysplasia related to PRKG2. | 0 |
| 33106379 | 2022 | Biallelic cGMP-dependent type II protein kinase gene (PRKG2) variants cause a novel acromesomelic dysplasia. | 6 |
| 34782440 | 2022 | Variable skeletal phenotypes associated with biallelic variants in PRKG2. | 3 |
| 33106379 | 2022 | Biallelic cGMP-dependent type II protein kinase gene (PRKG2) variants cause a novel acromesomelic dysplasia. | 6 |
| 34782440 | 2022 | Variable skeletal phenotypes associated with biallelic variants in PRKG2. | 3 |
| 32521860 | 2020 | Expression of PKG2 in ovarian cancer and its effect on epidermal growth factor receptor. | 2 |
| 32521860 | 2020 | Expression of PKG2 in ovarian cancer and its effect on epidermal growth factor receptor. | 2 |
| 31395339 | 2019 | Type II cGMP-dependent protein kinase phosphorylates EGFR at threonine 669 and thereby inhibits its activation. | 5 |
| 31395339 | 2019 | Type II cGMP-dependent protein kinase phosphorylates EGFR at threonine 669 and thereby inhibits its activation. | 5 |
| 29401205 | 2018 | Protein Kinases Type II (PKG II) Combined with L-Arginine Significantly Ameliorated Xenograft Tumor Development: Is L-Arginine a Potential Alternative in PKG II Activation? | 0 |
| 29517905 | 2018 | Neutron Crystallography Detects Differences in Protein Dynamics: Structure of the PKG II Cyclic Nucleotide Binding Domain in Complex with an Activator. | 0 |
| 29401205 | 2018 | Protein Kinases Type II (PKG II) Combined with L-Arginine Significantly Ameliorated Xenograft Tumor Development: Is L-Arginine a Potential Alternative in PKG II Activation? | 0 |
| 29517905 | 2018 | Neutron Crystallography Detects Differences in Protein Dynamics: Structure of the PKG II Cyclic Nucleotide Binding Domain in Complex with an Activator. | 0 |
| 28793191 | 2017 | Structural Basis of Analog Specificity in PKG I and II. | 7 |
Citation
Dessen P
PRKG2 (protein kinase cGMP-dependent 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41865/prkg2-(protein-kinase-cgmp-dependent-2)
