Identity
HGNC
LOCATION
8p21.2
LOCUSID
ALIAS
CADTK,CAKB,FADK2,FAK2,PKB,PTK,PYK2,RAFTK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2185
MIM: 601212
HGNC: 9612
Ensembl: ENSG00000120899
Variants:
dbSNP: 2185
ClinVar: 2185
TCGA: ENSG00000120899
COSMIC: PTK2B
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37586982 | 2024 | PYK2, a hub of signaling networks in breast cancer progression. | 3 |
| 37586982 | 2024 | PYK2, a hub of signaling networks in breast cancer progression. | 3 |
| 36470481 | 2023 | Wide-spread enhancer effect of SNP rs2279590 on regulating epoxide hydrolase-2 and protein tyrosine kinase 2-beta gene expression. | 2 |
| 37098808 | 2023 | The role and molecular mechanism of metabolic reprogramming of colorectal cancer by UBR5 through PYK2 regulation of OXPHOS expression study. | 1 |
| 37269155 | 2023 | PTK2B regulates immune responses of neutrophils and protects mucosal inflammation in ulcerative colitis. | 3 |
| 37487877 | 2023 | The regulation of human organic anion transporter 4 by insulin-like growth factor 1 and protein kinase B signaling. | 1 |
| 37894811 | 2023 | Thrombin-Induced COX-2 Expression and PGE(2) Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCδ/Pyk2-Dependent AP-1 Pathway Modulation. | 1 |
| 38321895 | 2023 | Microglia PTK2B/Pyk2 in the Pathogenesis of Alzheimer's Disease. | 1 |
| 36470481 | 2023 | Wide-spread enhancer effect of SNP rs2279590 on regulating epoxide hydrolase-2 and protein tyrosine kinase 2-beta gene expression. | 2 |
| 37098808 | 2023 | The role and molecular mechanism of metabolic reprogramming of colorectal cancer by UBR5 through PYK2 regulation of OXPHOS expression study. | 1 |
| 37269155 | 2023 | PTK2B regulates immune responses of neutrophils and protects mucosal inflammation in ulcerative colitis. | 3 |
| 37487877 | 2023 | The regulation of human organic anion transporter 4 by insulin-like growth factor 1 and protein kinase B signaling. | 1 |
| 37894811 | 2023 | Thrombin-Induced COX-2 Expression and PGE(2) Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCδ/Pyk2-Dependent AP-1 Pathway Modulation. | 1 |
| 38321895 | 2023 | Microglia PTK2B/Pyk2 in the Pathogenesis of Alzheimer's Disease. | 1 |
| 34905657 | 2022 | Role of proline-rich tyrosine kinase 2 (Pyk2) in the pathogenesis of Alzheimer's disease. | 0 |
Citation
Dessen P
PTK2B (protein tyrosine kinase 2 beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41899/ptk2b-(protein-tyrosine-kinase-2-beta)
