Identity
HGNC
LOCATION
12q15
LOCUSID
ALIAS
HPTP-BETA,HPTPB,PTPB,R-PTP-BETA,VEPTP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5787
MIM: 176882
HGNC: 9665
Ensembl: ENSG00000127329
Variants:
dbSNP: 5787
ClinVar: 5787
TCGA: ENSG00000127329
COSMIC: PTPRB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36148623 | 2023 | Novel rare mutation in a conserved site of PTPRB causes human hypoplastic left heart syndrome. | 2 |
| 36148623 | 2023 | Novel rare mutation in a conserved site of PTPRB causes human hypoplastic left heart syndrome. | 2 |
| 36397361 | 2022 | The variants in PTPRB, TRAF3IP3, and DISC1 genes were associated with Graves' disease in the Chinese population. | 1 |
| 36397361 | 2022 | The variants in PTPRB, TRAF3IP3, and DISC1 genes were associated with Graves' disease in the Chinese population. | 1 |
| 32663515 | 2020 | PSMD11, PTPRM and PTPRB as novel biomarkers of pancreatic cancer progression. | 13 |
| 32663515 | 2020 | PSMD11, PTPRM and PTPRB as novel biomarkers of pancreatic cancer progression. | 13 |
| 31040266 | 2019 | PTPRB promotes metastasis of colorectal carcinoma via inducing epithelial-mesenchymal transition. | 9 |
| 31125141 | 2019 | Exploring the effect of inhibitor AKB-9778 on VE-PTP by molecular docking and molecular dynamics simulation. | 8 |
| 31427368 | 2019 | Vascular Endothelial Receptor Tyrosine Phosphatase: Identification of Novel Substrates Related to Junctions and a Ternary Complex with EPHB4 and TIE2. | 10 |
| 31829261 | 2019 | miR-624-5p promoted tumorigenesis and metastasis by suppressing hippo signaling through targeting PTPRB in osteosarcoma cells. | 26 |
| 31040266 | 2019 | PTPRB promotes metastasis of colorectal carcinoma via inducing epithelial-mesenchymal transition. | 9 |
| 31125141 | 2019 | Exploring the effect of inhibitor AKB-9778 on VE-PTP by molecular docking and molecular dynamics simulation. | 8 |
| 31427368 | 2019 | Vascular Endothelial Receptor Tyrosine Phosphatase: Identification of Novel Substrates Related to Junctions and a Ternary Complex with EPHB4 and TIE2. | 10 |
| 31829261 | 2019 | miR-624-5p promoted tumorigenesis and metastasis by suppressing hippo signaling through targeting PTPRB in osteosarcoma cells. | 26 |
| 30044046 | 2018 | Collagen regulates the ability of endothelial progenitor cells to protect hypoxic myocardium through a mechanism involving miR-377/VE-PTP axis. | 3 |
Citation
Dessen P
PTPRB (protein tyrosine phosphatase receptor type B)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41924/ptprb-(protein-tyrosine-phosphatase-receptor-type-b)
