Identity
HGNC
LOCATION
1p35.3
LOCUSID
ALIAS
FMI,PCP-2,PTP,PTP-J,PTP-PI,PTP-RO,PTPPSI,PTPRO,PTPU2,R-PTP-PSI,R-PTP-U,hPTP-J
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10076
MIM: 602454
HGNC: 9683
Ensembl: ENSG00000060656
Variants:
dbSNP: 10076
ClinVar: 10076
TCGA: ENSG00000060656
COSMIC: PTPRU
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000060656 | ENST00000345512 | Q92729 |
| ENSG00000060656 | ENST00000373779 | Q92729 |
| ENSG00000060656 | ENST00000428026 | Q92729 |
| ENSG00000060656 | ENST00000460170 | Q92729 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by SCF-KIT | REACTOME | R-HSA-1433557 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36332481 | 2022 | PTPRU, a quiescence-induced receptor tyrosine phosphatase negatively regulates osteogenic differentiation of human mesenchymal stem cells. | 0 |
| 36332481 | 2022 | PTPRU, a quiescence-induced receptor tyrosine phosphatase negatively regulates osteogenic differentiation of human mesenchymal stem cells. | 0 |
| 32591542 | 2020 | The receptor PTPRU is a redox sensitive pseudophosphatase. | 11 |
| 32591542 | 2020 | The receptor PTPRU is a redox sensitive pseudophosphatase. | 11 |
| 27761023 | 2016 | MicroRNA-574-5p promotes metastasis of non-small cell lung cancer by targeting PTPRU. | 38 |
| 27761023 | 2016 | MicroRNA-574-5p promotes metastasis of non-small cell lung cancer by targeting PTPRU. | 38 |
| 24876153 | 2014 | Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility. | 18 |
| 25337216 | 2014 | Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells. | 9 |
| 24876153 | 2014 | Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility. | 18 |
| 25337216 | 2014 | Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells. | 9 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19528353 | 2009 | Decreased nephrin and GLEPP-1, but increased VEGF, Flt-1, and nitrotyrosine, expressions in kidney tissue sections from women with preeclampsia. | 24 |
| 19528353 | 2009 | Decreased nephrin and GLEPP-1, but increased VEGF, Flt-1, and nitrotyrosine, expressions in kidney tissue sections from women with preeclampsia. | 24 |
| 16564554 | 2006 | Expression of synaptopodin and GLEPP1 as markers of steroid responsiveness in primary focal segmental glomerulosclerosis. | 8 |
Citation
Dessen P
PTPRU (protein tyrosine phosphatase receptor type U)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/41940/ptpru-(protein-tyrosine-phosphatase-receptor-type-u)
