PUM1 (pumilio RNA binding family member 1)

2003-05-01  

Identity

HGNC
PUM1
LOCATION
1p35.2
LOCUSID
9698
ALIAS
HSPUM,PUMH,PUMH1,PUML1,SCA47
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9698
MIM: 607204
HGNC: 14957
Ensembl: ENSG00000134644

Variants:

dbSNP: 9698
ClinVar: 9698
TCGA: ENSG00000134644
COSMIC: PUM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134644ENST00000257075Q14671
ENSG00000134644ENST00000373741Q5T1Z8
ENSG00000134644ENST00000373742Q14671
ENSG00000134644ENST00000373747Q5T1Z4
ENSG00000134644ENST00000424085E9PR38
ENSG00000134644ENST00000426105Q14671
ENSG00000134644ENST00000440538Q14671
ENSG00000134644ENST00000480602E9PMX1
ENSG00000134644ENST00000498419H0YDK8
ENSG00000134644ENST00000525843H0YEH2
ENSG00000134644ENST00000525948E9PM68
ENSG00000134644ENST00000525997H0YDC5
ENSG00000134644ENST00000526215E9PM68
ENSG00000134644ENST00000527498H0YCK1
ENSG00000134644ENST00000529846H0YC97
ENSG00000134644ENST00000530669H0YDQ6
ENSG00000134644ENST00000531867E9PL65
ENSG00000134644ENST00000532678H0YED4

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
trans-Golgi Network Vesicle BuddingREACTOMER-HSA-199992
Clathrin derived vesicle buddingREACTOMER-HSA-421837
Golgi Associated Vesicle BiogenesisREACTOMER-HSA-432722

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
380295392024Pumilio1 regulates NPM3/NPM1 axis to promote PD-L1-mediated immune escape in gastric cancer.0
382756052024A Circular RNA Derived from the Pumilio 1 Gene Could Regulate PTEN in Human Cumulus Cells.0
384715232024PUM1 and PGK1 are Favorable Housekeeping Genes over Established Biodosimetry-related Housekeeping Genes such as HPRT1, ITFG1, DPM1, MRPS5, 18S rRNA and Others after Radiation Exposure.0
380295392024Pumilio1 regulates NPM3/NPM1 axis to promote PD-L1-mediated immune escape in gastric cancer.0
382756052024A Circular RNA Derived from the Pumilio 1 Gene Could Regulate PTEN in Human Cumulus Cells.0
384715232024PUM1 and PGK1 are Favorable Housekeeping Genes over Established Biodosimetry-related Housekeeping Genes such as HPRT1, ITFG1, DPM1, MRPS5, 18S rRNA and Others after Radiation Exposure.0
374690182023PUM1 Promotes Tumor Progression by Activating DEPTOR-Meditated Glycolysis in Gastric Cancer.3
374690182023PUM1 Promotes Tumor Progression by Activating DEPTOR-Meditated Glycolysis in Gastric Cancer.3
350341012022TLR4 downregulation by the RNA-binding protein PUM1 alleviates cellular aging and osteoarthritis.31
355072032022PUMILIO-mediated translational control of somatic cell cycle program promotes folliculogenesis and contributes to ovarian cancer progression.0
356670932022PUM1 mediates the posttranscriptional regulation of human fetal hemoglobin.2
357362182022PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing.5
350341012022TLR4 downregulation by the RNA-binding protein PUM1 alleviates cellular aging and osteoarthritis.31
355072032022PUMILIO-mediated translational control of somatic cell cycle program promotes folliculogenesis and contributes to ovarian cancer progression.0
356670932022PUM1 mediates the posttranscriptional regulation of human fetal hemoglobin.2

Citation

Dessen P

PUM1 (pumilio RNA binding family member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41949/pum1-(pumilio-rna-binding-family-member-1)