RAB1A (RAB1A, member RAS oncogene family)

2003-02-01  

Identity

HGNC
LOCATION
2p14
LOCUSID
ALIAS
RAB1,YPT1
FUSION GENES

Other Information

Locus ID:

NCBI: 5861
MIM: 179508
HGNC: 9758
Ensembl: ENSG00000138069

Variants:

dbSNP: 5861
ClinVar: 5861
TCGA: ENSG00000138069
COSMIC: RAB1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138069ENST00000398529P62820
ENSG00000138069ENST00000409751E7END7
ENSG00000138069ENST00000409784P62820
ENSG00000138069ENST00000409784Q5U0I6
ENSG00000138069ENST00000409892P62820
ENSG00000138069ENST00000649427P62820
ENSG00000138069ENST00000649427Q5U0I6

Expression (GTEx)

0
50
100
150
200
250
300

Pathways

PathwaySourceExternal ID
LegionellosisKEGGko05134
LegionellosisKEGGhsa05134
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
COPII (Coat Protein 2) Mediated Vesicle TransportREACTOMER-HSA-204005
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic ProphaseREACTOMER-HSA-68875
Golgi Cisternae Pericentriolar Stack ReorganizationREACTOMER-HSA-162658
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-dependent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811434
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380404022024Deubiquitinating enzyme PSMD7 promotes bladder cancer development: Involvement of RAB1A stabilization.2
380404022024Deubiquitinating enzyme PSMD7 promotes bladder cancer development: Involvement of RAB1A stabilization.2
366023432023Subcellular Distribution of BALF2 and the Role of Rab1 in the Formation of Epstein-Barr Virus Cytoplasmic Assembly Compartment and Virion Release.3
371173312023Prognosis value and positive association of Rab1A/IL4Rα aberrant expression in gastric cancer.0
379248092023RAB1A haploinsufficiency phenocopies the 2p14-p15 microdeletion and is associated with impaired neuronal differentiation.1
366023432023Subcellular Distribution of BALF2 and the Role of Rab1 in the Formation of Epstein-Barr Virus Cytoplasmic Assembly Compartment and Virion Release.3
371173312023Prognosis value and positive association of Rab1A/IL4Rα aberrant expression in gastric cancer.0
379248092023RAB1A haploinsufficiency phenocopies the 2p14-p15 microdeletion and is associated with impaired neuronal differentiation.1
351818432022Circ_0061140 Contributes to the Malignant Progression in Ovarian Cancer Cells by Mediating the RAB1A Level Through Sponging miR-361-5p.5
362550682022Circ_0026123 promotes cisplatin resistance and progression of ovarian cancer by upregulating RAB1A through sequestering miR-543.6
365660182022SGOL2 promotes prostate cancer progression by inhibiting RAB1A ubiquitination.1
351818432022Circ_0061140 Contributes to the Malignant Progression in Ovarian Cancer Cells by Mediating the RAB1A Level Through Sponging miR-361-5p.5
362550682022Circ_0026123 promotes cisplatin resistance and progression of ovarian cancer by upregulating RAB1A through sequestering miR-543.6
365660182022SGOL2 promotes prostate cancer progression by inhibiting RAB1A ubiquitination.1
330744772021Ubiquitin-specific protease 2a promotes hepatocellular carcinoma progression via deubiquitination and stabilization of RAB1A.10

Citation

Dessen P

RAB1A (RAB1A, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41962/rab1a-(rab1a-member-ras-oncogene-family)