RAB30 (RAB30, member RAS oncogene family)

2003-12-01 Dessen P Affiliation

Identity

HGNC

RAB30

LOCATION

11q14.1

LOCUSID

27314

ALIAS

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 27314
MIM: 605693
HGNC: 9770
Ensembl: ENSG00000137502

Variants:

dbSNP: 27314
ClinVar: 27314
TCGA: ENSG00000137502
COSMIC: RAB30

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000137502	ENST00000260056	Q15771
ENSG00000137502	ENST00000260056	A8K5R1
ENSG00000137502	ENST00000524635	E9PI18
ENSG00000137502	ENST00000525117	E9PLM3
ENSG00000137502	ENST00000526205	E9PRF7
ENSG00000137502	ENST00000527633	Q15771
ENSG00000137502	ENST00000527633	A8K5R1
ENSG00000137502	ENST00000528379	E9PRX0
ENSG00000137502	ENST00000530224	E9PPW9
ENSG00000137502	ENST00000531021	E9PMJ1
ENSG00000137502	ENST00000532548	E9PNB9
ENSG00000137502	ENST00000533014	H0YDK7
ENSG00000137502	ENST00000533276	E9PQ07
ENSG00000137502	ENST00000533486	Q15771
ENSG00000137502	ENST00000533486	A8K5R1
ENSG00000137502	ENST00000534103	E9PJQ5
ENSG00000137502	ENST00000534141	Q15771
ENSG00000137502	ENST00000534301	E9PS06
ENSG00000137502	ENST00000612684	Q15771
ENSG00000137502	ENST00000612684	A8K5R1

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Vesicle-mediated transport	REACTOME	R-HSA-5653656
Membrane Trafficking	REACTOME	R-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER traffic	REACTOME	R-HSA-6811442
Intra-Golgi traffic	REACTOME	R-HSA-6811438
RAB geranylgeranylation	REACTOME	R-HSA-8873719

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
33359467	2021	A role for Rab30 in retrograde trafficking and maintenance of endosome-TGN organization.	8
33359467	2021	A role for Rab30 in retrograde trafficking and maintenance of endosome-TGN organization.	8
30290718	2019	RAB30 regulates PI4KB (phosphatidylinositol 4-kinase beta)-dependent autophagy against group A Streptococcus.	10
30290718	2019	RAB30 regulates PI4KB (phosphatidylinositol 4-kinase beta)-dependent autophagy against group A Streptococcus.	10
23615442	2013	Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole.	56
23615442	2013	Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole.	56
22188167	2012	Rab30 is required for the morphological integrity of the Golgi apparatus.	28
22188167	2012	Rab30 is required for the morphological integrity of the Golgi apparatus.	28

Citation

Dessen P

RAB30 (RAB30, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41977/rab30-(rab30-member-ras-oncogene-family)