RAB3D (RAB3D, member RAS oncogene family)

2003-02-01  

Identity

HGNC
RAB3D
LOCATION
19p13.2
LOCUSID
9545
ALIAS
D2-2,GOV,RAB16,RAD3D
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9545
MIM: 604350
HGNC: 9779
Ensembl: ENSG00000105514

Variants:

dbSNP: 9545
ClinVar: 9545
TCGA: ENSG00000105514
COSMIC: RAB3D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105514ENST00000222120O95716
ENSG00000105514ENST00000222120A0A024R7G2
ENSG00000105514ENST00000589655O95716
ENSG00000105514ENST00000589655A0A024R7G2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Pancreatic secretionKEGGko04972
Pancreatic secretionKEGGhsa04972
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
368562122023[miR-125b-5p inhibits proliferation and migration of osteosarcoma cells by negatively regulating RAB3D expression].0
375591402023CircECE1 promotes osteosarcoma progression through regulating RAB3D by sponging miR-588.1
368562122023[miR-125b-5p inhibits proliferation and migration of osteosarcoma cells by negatively regulating RAB3D expression].0
375591402023CircECE1 promotes osteosarcoma progression through regulating RAB3D by sponging miR-588.1
355498132022Hsa_circ_0103232 promotes melanoma cells proliferation and invasion via targeting miR-661/RAB3D.0
356168072022Hsa_circ_0006732 regulates colorectal cancer cell proliferation, invasion and EMT by miR-127-5p/RAB3D axis.7
355498132022Hsa_circ_0103232 promotes melanoma cells proliferation and invasion via targeting miR-661/RAB3D.0
356168072022Hsa_circ_0006732 regulates colorectal cancer cell proliferation, invasion and EMT by miR-127-5p/RAB3D axis.7
338912672021Long non-coding RNA FGD5-AS1 enhances osteosarcoma cell proliferation and migration by targeting miR-506-3p/RAB3D axis.9
339828322021Rab3 proteins and cancer: Exit strategies.10
345510922021GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies.13
338912672021Long non-coding RNA FGD5-AS1 enhances osteosarcoma cell proliferation and migration by targeting miR-506-3p/RAB3D axis.9
339828322021Rab3 proteins and cancer: Exit strategies.10
345510922021GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies.13
284727552017Silencing of Rab3D suppresses the proliferation and invasion of esophageal squamous cell carcinoma cells.17

Citation

Dessen P

RAB3D (RAB3D, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41992/rab3d-(rab3d-member-ras-oncogene-family)