Identity
HGNC
LOCATION
1q42.13
LOCUSID
ALIAS
HRES-1,HRES-1/RAB4,HRES1,RAB4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5867
MIM: 179511
HGNC: 9781
Ensembl: ENSG00000168118
Variants:
dbSNP: 5867
ClinVar: 5867
TCGA: ENSG00000168118
COSMIC: RAB4A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168118 | ENST00000366690 | P20338 |
| ENSG00000168118 | ENST00000366690 | A0A024R3U9 |
| ENSG00000168118 | ENST00000618010 | A0A087WYT5 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37423034 | 2023 | Receptor-mediated internalization promotes increased endosome size and number in a RAB4- and RAB5-dependent manner. | 0 |
| 37423034 | 2023 | Receptor-mediated internalization promotes increased endosome size and number in a RAB4- and RAB5-dependent manner. | 0 |
| 36307864 | 2022 | RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation. | 0 |
| 36307864 | 2022 | RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation. | 0 |
| 32019812 | 2020 | Complex Rab4-Mediated Regulation of Endosomal Size and EGFR Activation. | 14 |
| 32967969 | 2020 | Agonist-activated glucagon receptors are deubiquitinated at early endosomes by two distinct deubiquitinases to facilitate Rab4a-dependent recycling. | 9 |
| 32019812 | 2020 | Complex Rab4-Mediated Regulation of Endosomal Size and EGFR Activation. | 14 |
| 32967969 | 2020 | Agonist-activated glucagon receptors are deubiquitinated at early endosomes by two distinct deubiquitinases to facilitate Rab4a-dependent recycling. | 9 |
| 31575663 | 2019 | L-type prostaglandin D synthase regulates the trafficking of the PGD(2) DP1 receptor by interacting with the GTPase Rab4. | 3 |
| 31575663 | 2019 | L-type prostaglandin D synthase regulates the trafficking of the PGD(2) DP1 receptor by interacting with the GTPase Rab4. | 3 |
| 28604748 | 2017 | Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasis. | 16 |
| 28604748 | 2017 | Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasis. | 16 |
| 26716952 | 2016 | Laminar Shear Stress Promotes Vascular Endothelial Cell Autophagy Through Upregulation with Rab4. | 13 |
| 26716952 | 2016 | Laminar Shear Stress Promotes Vascular Endothelial Cell Autophagy Through Upregulation with Rab4. | 13 |
| 26430212 | 2015 | Rabaptin5 is recruited to endosomes by Rab4 and Rabex5 to regulate endosome maturation. | 20 |
Citation
Dessen P
RAB4A (RAB4A, member RAS oncogene family)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41999/rab4a-(rab4a-member-ras-oncogene-family)
