RAB6B (RAB6B, member RAS oncogene family)

2003-12-01  

Identity

HGNC
LOCATION
3q22.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 51560
MIM: 615852
HGNC: 14902
Ensembl: ENSG00000154917

Variants:

dbSNP: 51560
ClinVar: 51560
TCGA: ENSG00000154917
COSMIC: RAB6B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154917ENST00000285208Q9NRW1
ENSG00000154917ENST00000460865C9JU14
ENSG00000154917ENST00000469959C9J0I2
ENSG00000154917ENST00000477759J3KR73
ENSG00000154917ENST00000486858Q9NRW1
ENSG00000154917ENST00000488969C9JB90
ENSG00000154917ENST00000543906Q9NRW1

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Retrograde transport at the Trans-Golgi-NetworkREACTOMER-HSA-6811440
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-independent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811436
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198
TBC/RABGAPsREACTOMER-HSA-8854214
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
180447442008Rab6 family proteins interact with the dynein light chain protein DYNLRB1.38
180447442008Rab6 family proteins interact with the dynein light chain protein DYNLRB1.38
177073692007A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells.31
177073692007A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells.31
167909282006The structure of human neuronal Rab6B in the active and inactive form.10
167909282006The structure of human neuronal Rab6B in the active and inactive form.10

Citation

Dessen P

RAB6B (RAB6B, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/42005/rab6b-(rab6b-member-ras-oncogene-family)