Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4218
MIM: 165040
HGNC: 7007
Ensembl: ENSG00000167461
Variants:
dbSNP: 4218
ClinVar: 4218
TCGA: ENSG00000167461
COSMIC: RAB8A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000167461 | ENST00000300935 | P61006 |
| ENSG00000167461 | ENST00000300935 | A0A024R7I3 |
| ENSG00000167461 | ENST00000586682 | P61006 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38135900 | 2024 | Targeting Rab-RILPL interactions as a strategy to downregulate pathogenic LRRK2 in Parkinson's disease. | 0 |
| 38307024 | 2024 | The LRRK2 kinase substrates RAB8a and RAB10 contribute complementary but distinct disease-relevant phenotypes in human neurons. | 0 |
| 38135900 | 2024 | Targeting Rab-RILPL interactions as a strategy to downregulate pathogenic LRRK2 in Parkinson's disease. | 0 |
| 38307024 | 2024 | The LRRK2 kinase substrates RAB8a and RAB10 contribute complementary but distinct disease-relevant phenotypes in human neurons. | 0 |
| 36815135 | 2023 | Transcription Activation of Rab8A by PEA3 Augments Progression of Esophagus Cancer by Activating the Wnt/β-Catenin Signaling Pathway. | 1 |
| 36907439 | 2023 | Rab8 and TNPO1 are ciliary transport adaptors for GTPase Arl13b by interacting with its RVEP motif containing ciliary targeting sequence. | 1 |
| 37582861 | 2023 | Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression. | 1 |
| 36815135 | 2023 | Transcription Activation of Rab8A by PEA3 Augments Progression of Esophagus Cancer by Activating the Wnt/β-Catenin Signaling Pathway. | 1 |
| 36907439 | 2023 | Rab8 and TNPO1 are ciliary transport adaptors for GTPase Arl13b by interacting with its RVEP motif containing ciliary targeting sequence. | 1 |
| 37582861 | 2023 | Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression. | 1 |
| 35435110 | 2022 | Circular RNA 0001823 aggravates the growth and metastasis of the cervical cancer cells through modulating the microRNA-613/RAB8A axis. | 3 |
| 35435110 | 2022 | Circular RNA 0001823 aggravates the growth and metastasis of the cervical cancer cells through modulating the microRNA-613/RAB8A axis. | 3 |
| 33561610 | 2021 | Quantitative Proteomics Reveals Association of Neuron Projection Development Genes ARF4, KIF5B, and RAB8A With Hirschsprung Disease. | 5 |
| 33603205 | 2021 | The Salmonella effector protein SopD targets Rab8 to positively and negatively modulate the inflammatory response. | 13 |
| 34052089 | 2021 | Down-regulation of microRNA-30d-5p is associated with gestational diabetes mellitus by targeting RAB8A. | 8 |
Citation
Dessen P
RAB8A (RAB8A, member RAS oncogene family)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42009/rab8a-(rab8a-member-ras-oncogene-family)
