Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56852
MIM: 605256
HGNC: 18278
Ensembl: ENSG00000070950
Variants:
dbSNP: 56852
ClinVar: 56852
TCGA: ENSG00000070950
COSMIC: RAD18
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| DNA Repair | REACTOME | R-HSA-73894 |
| DNA Damage Bypass | REACTOME | R-HSA-73893 |
| Recognition of DNA damage by PCNA-containing replication complex | REACTOME | R-HSA-110314 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38073330 | 2024 | Transcription Factor E2F7 Hampers the Killing Effect of NK Cells against Colorectal Cancer Cells via Activating RAD18 Transcription. | 0 |
| 38073330 | 2024 | Transcription Factor E2F7 Hampers the Killing Effect of NK Cells against Colorectal Cancer Cells via Activating RAD18 Transcription. | 0 |
| 36634340 | 2023 | Implication of E3 ligase RAD18 in UV-induced mutagenesis in human induced pluripotent stem cells and neuronal progenitor cells. | 2 |
| 36634340 | 2023 | Implication of E3 ligase RAD18 in UV-induced mutagenesis in human induced pluripotent stem cells and neuronal progenitor cells. | 2 |
| 35115490 | 2022 | REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis. | 9 |
| 35313791 | 2022 | UBE2B promotes ovarian cancer growth via promoting RAD18 mediated ZMYM2 monoubiquitination and stabilization. | 7 |
| 35367987 | 2022 | Analysis of the Mechanism of RAD18 in Glioma. | 1 |
| 35426246 | 2022 | RAD18 confers radioresistance of esophagus squamous cell carcinoma through regulating p-DNA-PKcs. | 6 |
| 35459258 | 2022 | Genome-wide CRISPR screen identified Rad18 as a determinant of doxorubicin sensitivity in osteosarcoma. | 8 |
| 36480547 | 2022 | RAD18 opposes transcription-associated genome instability through FANCD2 recruitment. | 5 |
| 35115490 | 2022 | REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis. | 9 |
| 35313791 | 2022 | UBE2B promotes ovarian cancer growth via promoting RAD18 mediated ZMYM2 monoubiquitination and stabilization. | 7 |
| 35367987 | 2022 | Analysis of the Mechanism of RAD18 in Glioma. | 1 |
| 35426246 | 2022 | RAD18 confers radioresistance of esophagus squamous cell carcinoma through regulating p-DNA-PKcs. | 6 |
| 35459258 | 2022 | Genome-wide CRISPR screen identified Rad18 as a determinant of doxorubicin sensitivity in osteosarcoma. | 8 |
Citation
Dessen P
RAD18 (RAD18 E3 ubiquitin protein ligase)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42025/rad18
