MOK (MOK protein kinase)

2003-06-01  

Identity

HGNC
LOCATION
14q32.31
LOCUSID
ALIAS
RAGE,RAGE-1,RAGE1,STK30
FUSION GENES

Other Information

Locus ID:

NCBI: 5891
MIM: 605762
HGNC: 9833
Ensembl: ENSG00000080823

Variants:

dbSNP: 5891
ClinVar: 5891
TCGA: ENSG00000080823
COSMIC: MOK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000080823ENST00000361847Q9UQ07
ENSG00000080823ENST00000517537E5RI85
ENSG00000080823ENST00000517966H0YKX6
ENSG00000080823ENST00000518399E5RHY4
ENSG00000080823ENST00000518482E5RHY4
ENSG00000080823ENST00000519058E5RHT7
ENSG00000080823ENST00000520238E5RFX9
ENSG00000080823ENST00000521388E5RHY4
ENSG00000080823ENST00000521766E5RHY4
ENSG00000080823ENST00000521937H0YBV8
ENSG00000080823ENST00000522093E5RFX9
ENSG00000080823ENST00000522534E5RHT7
ENSG00000080823ENST00000522537H0YMY9
ENSG00000080823ENST00000522867H0YKX6
ENSG00000080823ENST00000522874Q9UQ07
ENSG00000080823ENST00000523231H0YKX6
ENSG00000080823ENST00000524207E5RFX9
ENSG00000080823ENST00000524214Q9UQ07
ENSG00000080823ENST00000524370H0YKX6
ENSG00000080823ENST00000559138H0YLZ5
ENSG00000080823ENST00000559838H0YM36
ENSG00000080823ENST00000561150H0YLZ5
ENSG00000080823ENST00000562292H3BNF8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

References

Pubmed IDYearTitleCitations
212649542011S100B attenuates microglia activation in gliomas: possible role of STAT3 pathway.24
242444862013Distinct expression patterns of ICK/MAK/MOK protein kinases in the intestine implicate functional diversity.8
245295642014Association of RAGE (p.Gly82Ser) and MnSOD (p.Val16Ala) polymorphisms with diabetic retinopathy in T2DM patients from north India.8
159006052005Generation of RAGE-1 and MAGE-9 peptide-specific cytotoxic T-lymphocyte lines for transfer in patients with renal cell carcinoma.7
186854872008The utility of PAX-2 in distinguishing metastatic clear cell renal cell carcinoma from its morphologic mimics: an immunohistochemical study with comparison to renal cell carcinoma marker.7
213773872011TLR4 and RAGE: similar routes leading to inflammation in type 2 diabetic patients.4
153279902004Cdx2 homeodomain protein regulates the expression of MOK, a member of the mitogen-activated protein kinase superfamily, in the intestinal epithelial cells.3
190600052009Targeted resequencing of two genes, RAGE and POLL, confirms findings from a genome-wide scan for adaptive evolution and provides evidence for positive selection in additional populations.2
257556992015MOK overexpression is associated with promoter hypomethylation in patients with acute myeloid leukemia.2
217172462012Overexpression of renal tumor antigen is associated with tumor invasion and poor prognosis of hepatocellular carcinoma.1

Citation

Dessen P

MOK (MOK protein kinase)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42034/mok-(mok-protein-kinase)