Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5898
MIM: 179550
HGNC: 9839
Ensembl: ENSG00000006451
Variants:
dbSNP: 5898
ClinVar: 5898
TCGA: ENSG00000006451
COSMIC: RALA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000006451 | ENST00000005257 | P11233 |
| ENSG00000006451 | ENST00000434466 | H7C3P7 |
| ENSG00000006451 | ENST00000436179 | C9JPE8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38286821 | 2024 | Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation. | 2 |
| 38286821 | 2024 | Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation. | 2 |
| 36817861 | 2023 | Identification of RALA as a Therapeutic Target and Prognostic Predictor of Osteosarcoma. | 0 |
| 37116704 | 2023 | Ral GTPase promotes metastasis of pancreatic ductal adenocarcinoma via elevation of TGF-β1 production. | 1 |
| 36817861 | 2023 | Identification of RALA as a Therapeutic Target and Prognostic Predictor of Osteosarcoma. | 0 |
| 37116704 | 2023 | Ral GTPase promotes metastasis of pancreatic ductal adenocarcinoma via elevation of TGF-β1 production. | 1 |
| 34767674 | 2022 | Dysregulation of RalA signaling through dual regulatory mechanisms exerts its oncogenic functions in hepatocellular carcinoma. | 5 |
| 34767674 | 2022 | Dysregulation of RalA signaling through dual regulatory mechanisms exerts its oncogenic functions in hepatocellular carcinoma. | 5 |
| 34009715 | 2021 | Ral GTPase-activating protein regulates the malignancy of pancreatic ductal adenocarcinoma. | 7 |
| 34096503 | 2021 | RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis. | 8 |
| 34118960 | 2021 | The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer. | 4 |
| 34320341 | 2021 | RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal. | 7 |
| 34944458 | 2021 | RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth. | 0 |
| 34009715 | 2021 | Ral GTPase-activating protein regulates the malignancy of pancreatic ductal adenocarcinoma. | 7 |
| 34096503 | 2021 | RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis. | 8 |
Citation
Dessen P
RALA (RAS like proto-oncogene A)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42035/rala-(ras-like-proto-oncogene-a)
