Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 115727
MIM: 607320
HGNC: 18958
Ensembl: ENSG00000171777
Variants:
dbSNP: 115727
ClinVar: 115727
TCGA: ENSG00000171777
COSMIC: RASGRP4
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31409422 | 2019 | The critical role of RasGRP4 in the growth of diffuse large B cell lymphoma. | 4 |
| 31409422 | 2019 | The critical role of RasGRP4 in the growth of diffuse large B cell lymphoma. | 4 |
| 25330932 | 2015 | Ras guanine nucleotide-releasing protein 4 is aberrantly expressed in the fibroblast-like synoviocytes of patients with rheumatoid arthritis and controls their proliferation. | 10 |
| 25330932 | 2015 | Ras guanine nucleotide-releasing protein 4 is aberrantly expressed in the fibroblast-like synoviocytes of patients with rheumatoid arthritis and controls their proliferation. | 10 |
| 22728827 | 2012 | GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4. | 31 |
| 22728827 | 2012 | GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4. | 31 |
| 21933395 | 2011 | Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis. | 7 |
| 21933395 | 2011 | Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis. | 7 |
| 19350351 | 2009 | Possible involvement of RasGRP4 in leukemogenesis. | 8 |
| 19350351 | 2009 | Possible involvement of RasGRP4 in leukemogenesis. | 8 |
| 18024961 | 2008 | The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2. | 8 |
| 18024961 | 2008 | The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2. | 8 |
| 12493770 | 2003 | RasGRP4 regulates the expression of prostaglandin D2 in human and rat mast cell lines. | 14 |
| 12493770 | 2003 | RasGRP4 regulates the expression of prostaglandin D2 in human and rat mast cell lines. | 14 |
| 11880369 | 2002 | RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia. | 40 |
Citation
Dessen P
RASGRP4 (RAS guanyl releasing protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/42056/rasgrp4-(ras-guanyl-releasing-protein-4)
