Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5983
MIM: 600405
HGNC: 9971
Ensembl: ENSG00000133119
Variants:
dbSNP: 5983
ClinVar: 5983
TCGA: ENSG00000133119
COSMIC: RFC3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000133119 | ENST00000380071 | P40938 |
| ENSG00000133119 | ENST00000380071 | A0A024RDQ8 |
| ENSG00000133119 | ENST00000434425 | P40938 |
| ENSG00000133119 | ENST00000616236 | A0A087X270 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38383698 | 2024 | Abnormal activation of RFC3, A YAP1/TEAD downstream target, promotes gastric cancer progression. | 1 |
| 38383698 | 2024 | Abnormal activation of RFC3, A YAP1/TEAD downstream target, promotes gastric cancer progression. | 1 |
| 37861747 | 2023 | RFC3 serves as a novel prognostic biomarker and target for head and neck squamous cell carcinoma. | 2 |
| 37861747 | 2023 | RFC3 serves as a novel prognostic biomarker and target for head and neck squamous cell carcinoma. | 2 |
| 34930359 | 2021 | IRF2 inhibits ZIKV replication by promoting FAM111A expression to enhance the host restriction effect of RFC3. | 3 |
| 34930359 | 2021 | IRF2 inhibits ZIKV replication by promoting FAM111A expression to enhance the host restriction effect of RFC3. | 3 |
| 31661124 | 2019 | RFC3 induces epithelial‑mesenchymal transition in lung adenocarcinoma cells through the Wnt/β‑catenin pathway and possesses prognostic value in lung adenocarcinoma. | 17 |
| 31661124 | 2019 | RFC3 induces epithelial‑mesenchymal transition in lung adenocarcinoma cells through the Wnt/β‑catenin pathway and possesses prognostic value in lung adenocarcinoma. | 17 |
| 25541153 | 2015 | Replication factor C3 is a CREB target gene that regulates cell cycle progression through the modulation of chromatin loading of PCNA. | 25 |
| 26397132 | 2015 | shRNA-mediated silencing of the RFC3 gene suppresses hepatocellular carcinoma cell proliferation. | 14 |
| 26464638 | 2015 | ShRNA-mediated silencing of the RFC3 gene suppress ovarian tumor cells proliferation. | 13 |
| 25541153 | 2015 | Replication factor C3 is a CREB target gene that regulates cell cycle progression through the modulation of chromatin loading of PCNA. | 25 |
| 26397132 | 2015 | shRNA-mediated silencing of the RFC3 gene suppresses hepatocellular carcinoma cell proliferation. | 14 |
| 26464638 | 2015 | ShRNA-mediated silencing of the RFC3 gene suppress ovarian tumor cells proliferation. | 13 |
| 25030735 | 2014 | Overexpression of RFC3 is correlated with ovarian tumor development and poor prognosis. | 13 |
Citation
Dessen P
RFC3 (replication factor C subunit 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42089/rfc3-(replication-factor-c-subunit-3)
