TRAF7 (TNF receptor associated factor 7)

2004-04-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
CAFDADD,RFWD1,RNF119
FUSION GENES

Other Information

Locus ID:

NCBI: 84231
MIM: 606692
HGNC: 20456
Ensembl: ENSG00000131653

Variants:

dbSNP: 84231
ClinVar: 84231
TCGA: ENSG00000131653
COSMIC: TRAF7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131653ENST00000326181Q6Q0C0
ENSG00000131653ENST00000564067H3BUP4
ENSG00000131653ENST00000565383H3BUP4
ENSG00000131653ENST00000567645H3BR17
ENSG00000131653ENST00000567653A0A087WUB0

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
388140792024The Chlamydia trachomatis Inc Tri1 interacts with TRAF7 to displace native TRAF7 interacting partners.0
389276382024Expression of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Candidate Genes EDA2R, PCDH9, and TRAF7 in Normal Human Kidney Development and CAKUT.1
388140792024The Chlamydia trachomatis Inc Tri1 interacts with TRAF7 to displace native TRAF7 interacting partners.0
389276382024Expression of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Candidate Genes EDA2R, PCDH9, and TRAF7 in Normal Human Kidney Development and CAKUT.1
363954682023TRAF7-mutated Fibromyxoid Spindle Cell Tumors Are Associated With an Aggressive Clinical Course and Harbor an Undifferentiated Sarcoma Methylation Signature: A Molecular and Clinicopathologic Study of 3 Cases.1
370033492023TRAF7 inhibits glycolysis to potentiate growth inhibition and apoptosis of myeloid leukemia cells via regulating the KLF2-PFKFB3 axis.0
370435372023Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease.7
370673852023Novel mosaic TRAF7 likely pathogenic variant in an African American family.3
363954682023TRAF7-mutated Fibromyxoid Spindle Cell Tumors Are Associated With an Aggressive Clinical Course and Harbor an Undifferentiated Sarcoma Methylation Signature: A Molecular and Clinicopathologic Study of 3 Cases.1
370033492023TRAF7 inhibits glycolysis to potentiate growth inhibition and apoptosis of myeloid leukemia cells via regulating the KLF2-PFKFB3 axis.0
370435372023Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease.7
370673852023Novel mosaic TRAF7 likely pathogenic variant in an African American family.3
356849782022Prenatal diagnosis of a germline variant in TRAF7: Importance of accessibility to prenatal exome sequencing in cases of structural fetal anomalies.2
356849782022Prenatal diagnosis of a germline variant in TRAF7: Importance of accessibility to prenatal exome sequencing in cases of structural fetal anomalies.2
336674232021TRAF7 mutations and immunohistochemical study of uterine adenomatoid tumor compared with malignant mesothelioma.2

Citation

Dessen P

TRAF7 (TNF receptor associated factor 7)

Atlas Genet Cytogenet Oncol Haematol. 2004-04-01

Online version: http://atlasgeneticsoncology.org/gene/42094/traf7-(tnf-receptor-associated-factor-7)