Identity
HGNC
LOCATION
4p16.3
LOCUSID
ALIAS
RES4-26,SLX5,SNURF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6047
MIM: 602850
HGNC: 10067
Ensembl: ENSG00000063978
Variants:
dbSNP: 6047
ClinVar: 6047
TCGA: ENSG00000063978
COSMIC: RNF4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38340377 | 2024 | RNF4 prevents genomic instability caused by chronic DNA under-replication. | 1 |
| 38530355 | 2024 | RNF4 sustains Myc-driven tumorigenesis by facilitating DNA replication. | 1 |
| 38340377 | 2024 | RNF4 prevents genomic instability caused by chronic DNA under-replication. | 1 |
| 38530355 | 2024 | RNF4 sustains Myc-driven tumorigenesis by facilitating DNA replication. | 1 |
| 35007836 | 2022 | Roles of the SUMO-related enzymes, PIAS1, PIAS4, and RNF4, in DNA double-strand break repair by homologous recombination. | 2 |
| 35236966 | 2022 | RNF4 silencing induces cell growth arrest and DNA damage by promoting nuclear targeting of p62 in hepatocellular carcinoma. | 2 |
| 35622143 | 2022 | PRMT5-mediated RNF4 methylation promotes therapeutic resistance of APL cells to As(2)O(3) by stabilizing oncoprotein PML-RARα. | 2 |
| 35926659 | 2022 | RNF4 promotes tumorigenesis, therapy resistance of cholangiocarcinoma and affects cell cycle by regulating the ubiquitination degradation of p27kip1 in the nucleus. | 1 |
| 36153321 | 2022 | RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival. | 3 |
| 35007836 | 2022 | Roles of the SUMO-related enzymes, PIAS1, PIAS4, and RNF4, in DNA double-strand break repair by homologous recombination. | 2 |
| 35236966 | 2022 | RNF4 silencing induces cell growth arrest and DNA damage by promoting nuclear targeting of p62 in hepatocellular carcinoma. | 2 |
| 35622143 | 2022 | PRMT5-mediated RNF4 methylation promotes therapeutic resistance of APL cells to As(2)O(3) by stabilizing oncoprotein PML-RARα. | 2 |
| 35926659 | 2022 | RNF4 promotes tumorigenesis, therapy resistance of cholangiocarcinoma and affects cell cycle by regulating the ubiquitination degradation of p27kip1 in the nucleus. | 1 |
| 36153321 | 2022 | RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival. | 3 |
| 32197837 | 2020 | RNF4-mediated SUMO-targeted ubiquitination relieves PARIS/ZNF746-mediated transcriptional repression. | 5 |
Citation
Dessen P
RNF4 (ring finger protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42137/rnf4-(ring-finger-protein-4)
