Identity
HGNC
LOCATION
17q23.1
LOCUSID
ALIAS
PS6K,S6K,S6K-beta-1,S6K1,STK14A,p70
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6198
MIM: 608938
HGNC: 10436
Ensembl: ENSG00000108443
Variants:
dbSNP: 6198
ClinVar: 6198
TCGA: ENSG00000108443
COSMIC: RPS6KB1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37993085 | 2024 | IRGM is a novel regulator of PD-L1 via promoting S6K1-mediated phosphorylation of YBX1 in hepatocellular carcinoma. | 3 |
| 37993085 | 2024 | IRGM is a novel regulator of PD-L1 via promoting S6K1-mediated phosphorylation of YBX1 in hepatocellular carcinoma. | 3 |
| 36508123 | 2023 | Tumor P70S6K hyperactivation is inversely associated with tumor-infiltrating lymphocytes in triple-negative breast cancer. | 0 |
| 36803362 | 2023 | Prognostic and survival impact of BCL9 and RPS6KB1 copy number variation detected from circulating free DNA in hepatocellular carcinoma. | 1 |
| 37011005 | 2023 | EIF4A3 Acts on the PI3K-AKT-ERK1/2-P70S6K Pathway through FLOT1 to Influence the Development of Lung Adenocarcinoma. | 3 |
| 37014579 | 2023 | AMPK/mTOR/p70S6K axis prevents apoptosis of Porphyromonas gingivalis-infected gingival epithelial cells via Bad(Ser136) phosphorylation. | 2 |
| 37964239 | 2023 | Correlation and influencing factors analysis of colorectal polyps with Helicobacter pylori Infection and p-S6K1 expression. | 0 |
| 36508123 | 2023 | Tumor P70S6K hyperactivation is inversely associated with tumor-infiltrating lymphocytes in triple-negative breast cancer. | 0 |
| 36803362 | 2023 | Prognostic and survival impact of BCL9 and RPS6KB1 copy number variation detected from circulating free DNA in hepatocellular carcinoma. | 1 |
| 37011005 | 2023 | EIF4A3 Acts on the PI3K-AKT-ERK1/2-P70S6K Pathway through FLOT1 to Influence the Development of Lung Adenocarcinoma. | 3 |
| 37014579 | 2023 | AMPK/mTOR/p70S6K axis prevents apoptosis of Porphyromonas gingivalis-infected gingival epithelial cells via Bad(Ser136) phosphorylation. | 2 |
| 37964239 | 2023 | Correlation and influencing factors analysis of colorectal polyps with Helicobacter pylori Infection and p-S6K1 expression. | 0 |
| 34668023 | 2022 | Functional variants of RPS6KB1 and PIK3R1 in the autophagy pathway genes and risk of bladder cancer. | 2 |
| 34916228 | 2022 | Ribosomal protein S6 kinase beta-1 gene variants cause hypertrophic cardiomyopathy. | 1 |
| 35078109 | 2022 | Nuclear S6K1 regulates cAMP-responsive element-dependent gene transcription through activation of mTOR signal pathway. | 3 |
Citation
Dessen P
RPS6KB1 (ribosomal protein S6 kinase B1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42168/rps6kb1
