Identity
HGNC
LOCATION
1p36.11
LOCUSID
ALIAS
AML2,CBFA3,PEBP2aC
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 864
MIM: 600210
HGNC: 10473
Ensembl: ENSG00000020633
Variants:
dbSNP: 864
ClinVar: 864
TCGA: ENSG00000020633
COSMIC: RUNX3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Th1 and Th2 cell differentiation | KEGG | ko04658 |
| Th1 and Th2 cell differentiation | KEGG | hsa04658 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38009648 | 2024 | Differential Runx3, Eomes, and T-bet expression subdivides MS-associated CD4(+) T cells with brain-homing capacity. | 1 |
| 38197631 | 2024 | RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription. | 0 |
| 38240752 | 2024 | Aberrant Upregulation of RUNX3 Activates Developmental Genes to Drive Metastasis in Gastric Cancer. | 0 |
| 38424632 | 2024 | Ubiquitylation of RUNX3 by RNA-binding ubiquitin ligase MEX3C promotes tumorigenesis in lung adenocarcinoma. | 0 |
| 38704830 | 2024 | Downregulation of lncRNA MIR17HG reduced tumorigenicity and Treg-mediated immune escape of non-small-cell lung cancer cells through targeting the miR-17-5p/RUNX3 axis. | 0 |
| 38913281 | 2024 | RUNX3 exerts tumor-suppressive role through inhibiting EXOSC4 expression. | 0 |
| 38009648 | 2024 | Differential Runx3, Eomes, and T-bet expression subdivides MS-associated CD4(+) T cells with brain-homing capacity. | 1 |
| 38197631 | 2024 | RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription. | 0 |
| 38240752 | 2024 | Aberrant Upregulation of RUNX3 Activates Developmental Genes to Drive Metastasis in Gastric Cancer. | 0 |
| 38424632 | 2024 | Ubiquitylation of RUNX3 by RNA-binding ubiquitin ligase MEX3C promotes tumorigenesis in lung adenocarcinoma. | 0 |
| 38704830 | 2024 | Downregulation of lncRNA MIR17HG reduced tumorigenicity and Treg-mediated immune escape of non-small-cell lung cancer cells through targeting the miR-17-5p/RUNX3 axis. | 0 |
| 38913281 | 2024 | RUNX3 exerts tumor-suppressive role through inhibiting EXOSC4 expression. | 0 |
| 36596403 | 2023 | Genetically encoded Runx3 and CD4(+) intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy. | 1 |
| 36627006 | 2023 | Increased transcription of hsa_circ_0000644 upon RUNX family transcription factor 3 downregulation participates in the malignant development of bladder cancer. | 1 |
| 36759572 | 2023 | Runx1/3-driven adaptive endoplasmic reticulum stress pathways contribute to neurofibromagenesis. | 4 |
Citation
Dessen P
RUNX3 (RUNX family transcription factor 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42184
