RXRB (retinoid X receptor beta)

2003-08-01  

Identity

HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
DAUDI6,H-2RIIBP,NR2B2,RCoR-1
FUSION GENES

Other Information

Locus ID:

NCBI: 6257
MIM: 180246
HGNC: 10478
Ensembl: ENSG00000204231

Variants:

dbSNP: 6257
ClinVar: 6257
TCGA: ENSG00000204231
COSMIC: RXRB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204231ENST00000374680P28702
ENSG00000204231ENST00000374680Q5STP9
ENSG00000204231ENST00000374685P28702
ENSG00000204231ENST00000374685A0A0S2Z570
ENSG00000204231ENST00000483281E9PK75

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
PPAR signaling pathwayKEGGko03320
Adipocytokine signaling pathwayKEGGko04920
Thyroid cancerKEGGko05216
Small cell lung cancerKEGGko05222
Non-small cell lung cancerKEGGko05223
PPAR signaling pathwayKEGGhsa03320
Adipocytokine signaling pathwayKEGGhsa04920
Pathways in cancerKEGGhsa05200
Thyroid cancerKEGGhsa05216
Small cell lung cancerKEGGhsa05222
Non-small cell lung cancerKEGGhsa05223
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202
Thyroid hormone signaling pathwayKEGGhsa04919
Signal TransductionREACTOMER-HSA-162582
Signaling by Retinoic AcidREACTOMER-HSA-5362517
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Nuclear Receptor transcription pathwayREACTOMER-HSA-383280
Th17 cell differentiationKEGGko04659
Th17 cell differentiationKEGGhsa04659

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
156086922004Retinoid X receptors: X-ploring their (patho)physiological functions.89
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
192550642009Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.70
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.51
182171392008Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.34
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.32
186604892008Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.26
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.25
194532612009High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.20
223228852012A fatty acid-binding protein 7/RXRβ pathway enhances survival and proliferation in triple-negative breast cancer.19

Citation

Dessen P

RXRB (retinoid X receptor beta)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/42187/rxrb-(retinoid-x-receptor-beta)