S100A6 (S100 calcium binding protein A6)

2003-02-01  

Identity

HGNC
S100A6
LOCATION
1q21.3
LOCUSID
6277
ALIAS
2A9,5B10,CABP,CACY,PRA,S10A6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6277
MIM: 114110
HGNC: 10496
Ensembl: ENSG00000197956

Variants:

dbSNP: 6277
ClinVar: 6277
TCGA: ENSG00000197956
COSMIC: S100A6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197956ENST00000368719P06703
ENSG00000197956ENST00000368720P06703
ENSG00000197956ENST00000462776R4GN98
ENSG00000197956ENST00000496817P06703

Expression (GTEx)

0
500
1000
1500
2000
2500
3000
3500
4000
4500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383505472024S100A6 drives lymphatic metastasis of liver cancer via activation of the RAGE/NF-kB/VEGF-D pathway.0
387668162024Involvement of S100A6/S100A11 in T-Cell Immune Regulatory in HCC Revealed by Single Cell RNA-seq.0
388774132024S100A6 Regulates nucleus pulposus cell apoptosis via Wnt/β-catenin signaling pathway: an in vitro and in vivo study.0
383505472024S100A6 drives lymphatic metastasis of liver cancer via activation of the RAGE/NF-kB/VEGF-D pathway.0
387668162024Involvement of S100A6/S100A11 in T-Cell Immune Regulatory in HCC Revealed by Single Cell RNA-seq.0
388774132024S100A6 Regulates nucleus pulposus cell apoptosis via Wnt/β-catenin signaling pathway: an in vitro and in vivo study.0
366748732023S100A6 Protein-Expression and Function in Norm and Pathology.5
366809292023S100A6 promotes the development of thyroid cancer and inhibits apoptosis of thyroid cancer cells through the PI3K/AKT/mTOR pathway.0
367489832023S100A6 participates in initiation of autoimmune encephalitis and is under epigenetic control.1
372179452023S100A6 inhibits MDM2 to suppress breast cancer growth and enhance sensitivity to chemotherapy.0
375091752023The Role of S100A6 in Human Diseases: Molecular Mechanisms and Therapeutic Potential.6
376559802023The S100 calcium-binding protein A6 plays a crucial role in hepatic steatosis by mediating lipophagy.2
377597462023Interaction of S100A6 Protein with the Four-Helical Cytokines.0
366748732023S100A6 Protein-Expression and Function in Norm and Pathology.5
366809292023S100A6 promotes the development of thyroid cancer and inhibits apoptosis of thyroid cancer cells through the PI3K/AKT/mTOR pathway.0

Citation

Dessen P

S100A6 (S100 calcium binding protein A6)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42193/s100a6-(s100-calcium-binding-protein-a6)