Identity
HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
Ara1,HAF,HOMS1,SART1259,SNRNP110,Snu66
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9092
MIM: 605941
HGNC: 10538
Ensembl: ENSG00000175467
Variants:
dbSNP: 9092
ClinVar: 9092
TCGA: ENSG00000175467
COSMIC: SART1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000175467 | ENST00000312397 | O43290 |
| ENSG00000175467 | ENST00000530251 | E9PQI8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33391530 | 2021 | Suppressing Sart1 to modulate macrophage polarization by siRNA-loaded liposomes: a promising therapeutic strategy for pulmonary fibrosis. | 34 |
| 33391530 | 2021 | Suppressing Sart1 to modulate macrophage polarization by siRNA-loaded liposomes: a promising therapeutic strategy for pulmonary fibrosis. | 34 |
| 30705246 | 2019 | Hypoxia-Associated Factor (HAF) Mediates Neurofibromin Ubiquitination and Degradation Leading to Ras-ERK Pathway Activation in Hypoxia. | 13 |
| 30705246 | 2019 | Hypoxia-Associated Factor (HAF) Mediates Neurofibromin Ubiquitination and Degradation Leading to Ras-ERK Pathway Activation in Hypoxia. | 13 |
| 25915846 | 2016 | Mutant versions of von Hippel-Lindau (VHL) can protect HIF1α from SART1-mediated degradation in clear-cell renal cell carcinoma. | 4 |
| 28077916 | 2016 | Expression of Interferon Effector Gene SART1 Correlates with Interferon Treatment Response against Hepatitis B Infection. | 7 |
| 25915846 | 2016 | Mutant versions of von Hippel-Lindau (VHL) can protect HIF1α from SART1-mediated degradation in clear-cell renal cell carcinoma. | 4 |
| 28077916 | 2016 | Expression of Interferon Effector Gene SART1 Correlates with Interferon Treatment Response against Hepatitis B Infection. | 7 |
| 25481564 | 2015 | The spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing. | 21 |
| 25481564 | 2015 | The spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing. | 21 |
| 22027693 | 2012 | A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer. | 13 |
| 22027693 | 2012 | A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer. | 13 |
| 20056645 | 2010 | Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome. | 13 |
| 20056645 | 2010 | Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome. | 13 |
| 18374504 | 2008 | Influence of multiple genetic polymorphisms on genitourinary morbidity after carbon ion radiotherapy for prostate cancer. | 8 |
Citation
Dessen P
SART1 (spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42203/sart1-(spliceosome-associated-factor-1-recruiter-of-u4-u6-u5-tri-snrnp)
