SCGB1A1 (secretoglobin family 1A member 1)

2003-02-01  

Identity

HGNC
SCGB1A1
LOCATION
11q12.3
LOCUSID
7356
ALIAS
CC10,CC16,CCPBP,CCSP,UGB,UP-1,UP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7356
MIM: 192020
HGNC: 12523
Ensembl: ENSG00000149021

Variants:

dbSNP: 7356
ClinVar: 7356
TCGA: ENSG00000149021
COSMIC: SCGB1A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149021ENST00000278282P11684
ENSG00000149021ENST00000278282A0A0S2Z4R6
ENSG00000149021ENST00000534397E9PN95

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381105512024Club cell protein (CC16) in serum as an effect marker for small airway epithelial damage caused by diesel exhaust and blasting fumes in potash mining.0
381105512024Club cell protein (CC16) in serum as an effect marker for small airway epithelial damage caused by diesel exhaust and blasting fumes in potash mining.0
351684512023Club cell 10-kDa protein (CC10) as a surrogate for identifying type 2 asthma phenotypes.1
360666062023Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.10
375237102023Circulating CC16 and Asthma: A Population-based, Multicohort Study from Early Childhood through Adult Life.2
380539932023CC16 drives VLA-2-dependent SPLUNC1 expression.0
351684512023Club cell 10-kDa protein (CC10) as a surrogate for identifying type 2 asthma phenotypes.1
360666062023Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.10
375237102023Circulating CC16 and Asthma: A Population-based, Multicohort Study from Early Childhood through Adult Life.2
380539932023CC16 drives VLA-2-dependent SPLUNC1 expression.0
354394602022Urinary CC16, a potential indicator of lung integrity and inflammation, increases in children after short-term exposure to PM(2.5)/PM(10) and is driven by the CC16 38GG genotype.2
363117712022Brief Research Report: Serum clara cell 16 kDa protein levels are increased in patients hospitalized for severe SARS-CoV-2 or sepsis infection.1
363524222022CC16 polymorphisms in asthma, asthma subtypes, and asthma control in adults from the Agricultural Lung Health Study.1
354394602022Urinary CC16, a potential indicator of lung integrity and inflammation, increases in children after short-term exposure to PM(2.5)/PM(10) and is driven by the CC16 38GG genotype.2
363117712022Brief Research Report: Serum clara cell 16 kDa protein levels are increased in patients hospitalized for severe SARS-CoV-2 or sepsis infection.1

Citation

Dessen P

SCGB1A1 (secretoglobin family 1A member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42209/scgb1a1-(secretoglobin-family-1a-member-1)