CWC27 (CWC27 spliceosome associated cyclophilin)

2003-06-01  

Identity

HGNC
LOCATION
5q12.3
LOCUSID
ALIAS
NY-CO-10,RPSKA,SDCCAG-10,SDCCAG10
FUSION GENES

Other Information

Locus ID:

NCBI: 10283
MIM: 617170
HGNC: 10664
Ensembl: ENSG00000153015

Variants:

dbSNP: 10283
ClinVar: 10283
TCGA: ENSG00000153015
COSMIC: CWC27

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153015ENST00000381070Q6UX04
ENSG00000153015ENST00000508024D6REK3

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
367189962023Further delineation of the CWC27-associated spliceosomeopathy: Case report and review of the literature.0
367189962023Further delineation of the CWC27-associated spliceosomeopathy: Case report and review of the literature.0
323297752020Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.15
323297752020Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.15
282857692017Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies.41
282857692017Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies.41
272068502016Genome-Wide Association Study of Bladder Cancer in a Chinese Cohort Reveals a New Susceptibility Locus at 5q12.3.20
272068502016Genome-Wide Association Study of Bladder Cancer in a Chinese Cohort Reveals a New Susceptibility Locus at 5q12.3.20
254788302014Structure and evolution of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27.10
254788302014Structure and evolution of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27.10
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

CWC27 (CWC27 spliceosome associated cyclophilin)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42228/cwc27-(cwc27-spliceosome-associated-cyclophilin)