Identity
HGNC
LOCATION
Xp11.22
LOCUSID
ALIAS
CDA1,CINAP,CTCL,DENTT,HRIHFB2216,NP79,SE204,TSPX
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64061
MIM: 300564
HGNC: 24358
Ensembl: ENSG00000184205
Variants:
dbSNP: 64061
ClinVar: 64061
TCGA: ENSG00000184205
COSMIC: TSPYL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000184205 | ENST00000375442 | Q9H2G4 |
| ENSG00000184205 | ENST00000578306 | J3KST2 |
| ENSG00000184205 | ENST00000579390 | J3KS33 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38170390 | 2024 | CRL2(APPBP2)-mediated TSPYL2 degradation counteracts human mesenchymal stem cell senescence. | 3 |
| 38170390 | 2024 | CRL2(APPBP2)-mediated TSPYL2 degradation counteracts human mesenchymal stem cell senescence. | 3 |
| 36918555 | 2023 | Sex specific regulation of TSPY-Like 2 in the DNA damage response of cancer cells. | 3 |
| 37696385 | 2023 | A tumor-suppressing role of TSPYL2 in thyroid cancer: Through interacting with SIRT1 and repressing SIRT1/AKT pathway. | 0 |
| 36918555 | 2023 | Sex specific regulation of TSPY-Like 2 in the DNA damage response of cancer cells. | 3 |
| 37696385 | 2023 | A tumor-suppressing role of TSPYL2 in thyroid cancer: Through interacting with SIRT1 and repressing SIRT1/AKT pathway. | 0 |
| 35192400 | 2022 | TSPYL2 reduced gefitinib resistance and DNA damage repair via suppressing SIRT1-mediated FOXO3 deacetylation. | 3 |
| 35192400 | 2022 | TSPYL2 reduced gefitinib resistance and DNA damage repair via suppressing SIRT1-mediated FOXO3 deacetylation. | 3 |
| 33300073 | 2021 | hCINAP serves a critical role in hypoxia‑induced cardiomyocyte apoptosis via modulating lactate production and mitochondrial‑mediated apoptosis signaling. | 1 |
| 33300073 | 2021 | hCINAP serves a critical role in hypoxia‑induced cardiomyocyte apoptosis via modulating lactate production and mitochondrial‑mediated apoptosis signaling. | 1 |
| 30050056 | 2019 | TSPYL2 is a novel regulator of SIRT1 and p300 activity in response to DNA damage. | 19 |
| 30050056 | 2019 | TSPYL2 is a novel regulator of SIRT1 and p300 activity in response to DNA damage. | 19 |
| 29311219 | 2018 | Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1). | 11 |
| 29311219 | 2018 | Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1). | 11 |
| 28169398 | 2017 | The Y-located proto-oncogene TSPY exacerbates and its X-homologue TSPX inhibits transactivation functions of androgen receptor and its constitutively active variants. | 17 |
Citation
Dessen P
TSPYL2 (TSPY like 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42234/tspyl2-(tspy-like-2)
