Identity
HGNC
LOCATION
4q21.22
LOCUSID
ALIAS
ABP125,ABP130,HSPC275,HSPC334,NEDSOSB,SEC31L1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22872
MIM: 610257
HGNC: 17052
Ensembl: ENSG00000138674
Variants:
dbSNP: 22872
ClinVar: 22872
TCGA: ENSG00000138674
COSMIC: SEC31A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38400880 | 2024 | SEC31A may be associated with pituitary hormone deficiency and gonadal dysgenesis. | 0 |
| 38400880 | 2024 | SEC31A may be associated with pituitary hormone deficiency and gonadal dysgenesis. | 0 |
| 30464055 | 2019 | SEC31A mutation affects ER homeostasis, causing a neurological syndrome. | 15 |
| 30464055 | 2019 | SEC31A mutation affects ER homeostasis, causing a neurological syndrome. | 15 |
| 29604273 | 2018 | Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion. | 7 |
| 29604273 | 2018 | Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion. | 7 |
| 25540196 | 2015 | A new role for annexin A11 in the early secretory pathway via stabilizing Sec31A protein at the endoplasmic reticulum exit sites (ERES). | 24 |
| 25667979 | 2015 | Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2. | 17 |
| 25540196 | 2015 | A new role for annexin A11 in the early secretory pathway via stabilizing Sec31A protein at the endoplasmic reticulum exit sites (ERES). | 24 |
| 25667979 | 2015 | Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2. | 17 |
| 25006245 | 2014 | Apoptosis-linked gene-2 (ALG-2)/Sec31 interactions regulate endoplasmic reticulum (ER)-to-Golgi transport: a potential effector pathway for luminal calcium. | 24 |
| 25006245 | 2014 | Apoptosis-linked gene-2 (ALG-2)/Sec31 interactions regulate endoplasmic reticulum (ER)-to-Golgi transport: a potential effector pathway for luminal calcium. | 24 |
| 23349870 | 2013 | CK2 phosphorylates Sec31 and regulates ER-To-Golgi trafficking. | 35 |
| 24069399 | 2013 | ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex. | 23 |
| 23349870 | 2013 | CK2 phosphorylates Sec31 and regulates ER-To-Golgi trafficking. | 35 |
Citation
Dessen P
SEC31A (SEC31 homolog A, COPII coat complex component)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42237/sec31a-(sec31-homolog-a-copii-coat-complex-component)
