Identity
HGNC
LOCATION
6p25.3
LOCUSID
ALIAS
NEDFACH,SEC5,SEC5L1,Sec5p
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55770
MIM: 615329
HGNC: 24968
Ensembl: ENSG00000112685
Variants:
dbSNP: 55770
ClinVar: 55770
TCGA: ENSG00000112685
COSMIC: EXOC2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000112685 | ENST00000230449 | Q96KP1 |
| ENSG00000112685 | ENST00000230449 | A0A024QZT2 |
| ENSG00000112685 | ENST00000443083 | Q2MDF5 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32639540 | 2020 | Mutations in the exocyst component EXOC2 cause severe defects in human brain development. | 15 |
| 32639540 | 2020 | Mutations in the exocyst component EXOC2 cause severe defects in human brain development. | 15 |
| 26359301 | 2015 | Dexamethasone-induced cellular tension requires a SGK1-stimulated Sec5-GEF-H1 interaction. | 8 |
| 26359301 | 2015 | Dexamethasone-induced cellular tension requires a SGK1-stimulated Sec5-GEF-H1 interaction. | 8 |
| 23844030 | 2013 | Exocyst sec5 regulates exocytosis of newcomer insulin granules underlying biphasic insulin secretion. | 10 |
| 23844030 | 2013 | Exocyst sec5 regulates exocytosis of newcomer insulin granules underlying biphasic insulin secretion. | 10 |
| 22761837 | 2012 | Sec5 and Exo84 mediate distinct aspects of RalA-dependent cell polarization. | 10 |
| 22761837 | 2012 | Sec5 and Exo84 mediate distinct aspects of RalA-dependent cell polarization. | 10 |
| 21197618 | 2011 | Model-based prediction of human hair color using DNA variants. | 35 |
| 21197618 | 2011 | Model-based prediction of human hair color using DNA variants. | 35 |
| 20145037 | 2010 | Sec5 and Exo84 foster oncogenic ras-mediated tumorigenesis. | 22 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20570966 | 2010 | Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. | 181 |
| 20616560 | 2010 | Genetic differences between five European populations. | 18 |
| 20145037 | 2010 | Sec5 and Exo84 foster oncogenic ras-mediated tumorigenesis. | 22 |
Citation
Dessen P
EXOC2 (exocyst complex component 2)
Atlas Genet Cytogenet Oncol Haematol. 2004-02-01
Online version: http://atlasgeneticsoncology.org/gene/42239/exoc2-(exocyst-complex-component-2)
