Identity
HGNC
LOCATION
12q24.11
LOCUSID
ALIAS
CD162,CLA,PSGL-1,PSGL1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6404
MIM: 600738
HGNC: 10722
Ensembl: ENSG00000110876
Variants:
dbSNP: 6404
ClinVar: 6404
TCGA: ENSG00000110876
COSMIC: SELPLG
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000110876 | ENST00000228463 | Q14242 |
| ENSG00000110876 | ENST00000388962 | A0A0C4DFY0 |
| ENSG00000110876 | ENST00000550948 | Q14242 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38243063 | 2024 | PSGL-1 decorated with sialyl Lewis(a/x) promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement. | 0 |
| 38243063 | 2024 | PSGL-1 decorated with sialyl Lewis(a/x) promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement. | 0 |
| 37078358 | 2023 | The effects of SCARB2 and SELPLG gene polymorphisms on EV71 infection in hand, foot and mouth disease. | 0 |
| 37115668 | 2023 | PSGL-1 attenuates early TCR signaling to suppress CD8(+) T cell progenitor differentiation and elicit terminal CD8(+) T cell exhaustion. | 6 |
| 37463583 | 2023 | Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation. | 2 |
| 37787515 | 2023 | PSGL-1 is an evolutionarily conserved antiviral restriction factor. | 0 |
| 37819238 | 2023 | PSGL-1 Blockade Induces Classical Activation of Human Tumor-associated Macrophages. | 1 |
| 37854605 | 2023 | PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea. | 0 |
| 37078358 | 2023 | The effects of SCARB2 and SELPLG gene polymorphisms on EV71 infection in hand, foot and mouth disease. | 0 |
| 37115668 | 2023 | PSGL-1 attenuates early TCR signaling to suppress CD8(+) T cell progenitor differentiation and elicit terminal CD8(+) T cell exhaustion. | 6 |
| 37463583 | 2023 | Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation. | 2 |
| 37787515 | 2023 | PSGL-1 is an evolutionarily conserved antiviral restriction factor. | 0 |
| 37819238 | 2023 | PSGL-1 Blockade Induces Classical Activation of Human Tumor-associated Macrophages. | 1 |
| 37854605 | 2023 | PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea. | 0 |
| 33432452 | 2022 | P-Selectin Glycoprotein Ligand-1 Deficiency Protects Against Aortic Aneurysm Formation Induced by DOCA Plus Salt. | 4 |
Citation
Dessen P
SELPLG (selectin P ligand)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42251/selplg-(selectin-p-ligand)
