Identity
HGNC
LOCATION
18q21.33
LOCUSID
ALIAS
LEUPIN,PI11,SCCA-2,SCCA1,SCCA2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6318
MIM: 600518
HGNC: 10570
Ensembl: ENSG00000206073
Variants:
dbSNP: 6318
ClinVar: 6318
TCGA: ENSG00000206073
COSMIC: SERPINB4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000206073 | ENST00000341074 | P48594 |
| ENSG00000206073 | ENST00000413673 | H0Y5H9 |
| ENSG00000206073 | ENST00000436264 | C9JZ65 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Amoebiasis | KEGG | ko05146 |
| Amoebiasis | KEGG | hsa05146 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36791109 | 2023 | ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. | 5 |
| 36791109 | 2023 | ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. | 5 |
| 35537383 | 2022 | Differences in Thymus and Activation-Regulated Chemokine and Squamous Cell Carcinoma Antigen 2 Levels in Food Protein-Induced Enterocolitis Syndrome and Atopic Dermatitis. | 0 |
| 36301759 | 2022 | Increased expression of squamous cell carcinoma antigen 1 and 2 in mycosis fungoides and Sézary syndrome. | 0 |
| 35537383 | 2022 | Differences in Thymus and Activation-Regulated Chemokine and Squamous Cell Carcinoma Antigen 2 Levels in Food Protein-Induced Enterocolitis Syndrome and Atopic Dermatitis. | 0 |
| 36301759 | 2022 | Increased expression of squamous cell carcinoma antigen 1 and 2 in mycosis fungoides and Sézary syndrome. | 0 |
| 33839977 | 2021 | Clinical Significance of Serum Squamous Cell Carcinoma Antigen for Patients with Recurrent Esophageal Squamous Cell Carcinoma. | 5 |
| 34878006 | 2021 | Evaluation of squamous cell carcinoma antigen 1 expression in oral squamous cell carcinoma (tumor cells and peritumoral T-lymphocytes) and verrucous carcinoma and comparison with normal oral mucosa. | 7 |
| 33839977 | 2021 | Clinical Significance of Serum Squamous Cell Carcinoma Antigen for Patients with Recurrent Esophageal Squamous Cell Carcinoma. | 5 |
| 34878006 | 2021 | Evaluation of squamous cell carcinoma antigen 1 expression in oral squamous cell carcinoma (tumor cells and peritumoral T-lymphocytes) and verrucous carcinoma and comparison with normal oral mucosa. | 7 |
| 31815365 | 2020 | Measurement of squamous cell carcinoma antigen 2 in lichen planus patients. | 1 |
| 31815365 | 2020 | Measurement of squamous cell carcinoma antigen 2 in lichen planus patients. | 1 |
| 30078551 | 2019 | The clinical value of serum squamous cell carcinoma antigens 1 and 2 in head and neck squamous cell carcinoma. | 6 |
| 30825353 | 2019 | Squamous cell carcinoma antigen 1 is associated to poor prognosis in esophageal cancer through immune surveillance impairment and reduced chemosensitivity. | 17 |
| 30905447 | 2019 | Serum SCCA levels in patients suffering cancers or other diseases. | 8 |
Citation
Dessen P
SERPINB4 (serpin family B member 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42266/serpinb4-(serpin-family-b-member-4)
