Identity
HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
ESET,H3-K9-HMTase4,KG1T,KMT1E,TDRD21
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9869
MIM: 604396
HGNC: 10761
Ensembl: ENSG00000143379
Variants:
dbSNP: 9869
ClinVar: 9869
TCGA: ENSG00000143379
COSMIC: SETDB1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38159574 | 2024 | Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46. | 0 |
| 38317200 | 2024 | SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer. | 0 |
| 38426579 | 2024 | Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma. | 0 |
| 38583021 | 2024 | [Downregulation of SETDB1 suppresses epithelial mesenchymal transition and invasion and metastasis in oral cancer via SOX7 methylation]. | 0 |
| 38904842 | 2024 | SETDB1 deletion causes DNA demethylation and upregulation of multiple zinc-finger genes. | 0 |
| 38159574 | 2024 | Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46. | 0 |
| 38317200 | 2024 | SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer. | 0 |
| 38426579 | 2024 | Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma. | 0 |
| 38583021 | 2024 | [Downregulation of SETDB1 suppresses epithelial mesenchymal transition and invasion and metastasis in oral cancer via SOX7 methylation]. | 0 |
| 38904842 | 2024 | SETDB1 deletion causes DNA demethylation and upregulation of multiple zinc-finger genes. | 0 |
| 36524435 | 2023 | SETDB1: A perspective into immune cell function and cancer immunotherapy. | 2 |
| 36637424 | 2023 | SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors. | 7 |
| 36737533 | 2023 | Epigenetic inhibition of lncRNA GMDS-AS1 by methyltransferase ESET promoted cell viability and metastasis of hepatocellular carcinoma. | 0 |
| 36811655 | 2023 | Histone H3K9 methyltransferase SETDB1 overexpression correlates with pediatric high-grade gliomas progression and prognosis. | 2 |
| 36992419 | 2023 | Pregnancy Is Associated with Impaired Transcription of Human Endogenous Retroviruses and of TRIM28 and SETDB1, Particularly in Mothers Affected by Multiple Sclerosis. | 1 |
Citation
Dessen P
SETDB1 (SET domain bifurcated histone lysine methyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42273/setdb1-(set-domain-bifurcated-histone-lysine-methyltransferase-1)
