Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6425
MIM: 604158
HGNC: 10779
Ensembl: ENSG00000120057
Variants:
dbSNP: 6425
ClinVar: 6425
TCGA: ENSG00000120057
COSMIC: SFRP5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000120057 | ENST00000266066 | Q5T4F7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Wnt signaling pathway | KEGG | ko04310 |
| Wnt signaling pathway | KEGG | hsa04310 |
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164712563 | Bisphosphonates | Chemical | ClinicalAnnotation | associated | PD | ||
| PA445187 | Osteonecrosis | Disease | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38409837 | 2024 | SFRP5 Partially Inhibits the Proliferation and Migration of Airway Smooth Muscle Cells in Children with Asthma by Regulating the Wnt/β-Catenin Signaling Pathway. | 0 |
| 38714325 | 2024 | Secreted frizzled-related protein 5 overexpression reverses oxLDL-induced lipid accumulation in human vascular smooth muscle cells. | 0 |
| 38409837 | 2024 | SFRP5 Partially Inhibits the Proliferation and Migration of Airway Smooth Muscle Cells in Children with Asthma by Regulating the Wnt/β-Catenin Signaling Pathway. | 0 |
| 38714325 | 2024 | Secreted frizzled-related protein 5 overexpression reverses oxLDL-induced lipid accumulation in human vascular smooth muscle cells. | 0 |
| 36631199 | 2023 | Frizzled receptors and SFRP5 in lipid metabolism: Current findings and potential applications. | 1 |
| 37191968 | 2023 | TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis. | 0 |
| 36631199 | 2023 | Frizzled receptors and SFRP5 in lipid metabolism: Current findings and potential applications. | 1 |
| 37191968 | 2023 | TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis. | 0 |
| 34382203 | 2022 | Elevated Serum SFRP5 Levels During Preeclampsia and Its Potential Association with Trophoblast Dysfunction via Wnt/β-Catenin Suppression. | 6 |
| 34779987 | 2022 | The role of Wnt pathway antagonists in early-stage lung adenocarcinoma. | 3 |
| 35400241 | 2022 | Circulating level of serum secreted frizzled-related protein 5 decreases in polycystic ovary syndrome. | 0 |
| 36077270 | 2022 | Increased Secreted Frizzled-Related Protein 5 mRNA Expression in the Adipose Tissue of Women with Nonalcoholic Fatty Liver Disease Associated with Obesity. | 0 |
| 34382203 | 2022 | Elevated Serum SFRP5 Levels During Preeclampsia and Its Potential Association with Trophoblast Dysfunction via Wnt/β-Catenin Suppression. | 6 |
| 34779987 | 2022 | The role of Wnt pathway antagonists in early-stage lung adenocarcinoma. | 3 |
| 35400241 | 2022 | Circulating level of serum secreted frizzled-related protein 5 decreases in polycystic ovary syndrome. | 0 |
Citation
Dessen P
SFRP5 (secreted frizzled related protein 5)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42278/sfrp5-(secreted-frizzled-related-protein-5)
