SFRP5 (secreted frizzled related protein 5)

2003-11-01  

Identity

HGNC
SFRP5
LOCATION
10q24.2
LOCUSID
6425
ALIAS
SARP3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6425
MIM: 604158
HGNC: 10779
Ensembl: ENSG00000120057

Variants:

dbSNP: 6425
ClinVar: 6425
TCGA: ENSG00000120057
COSMIC: SFRP5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000120057ENST00000266066Q5T4F7

Expression (GTEx)

0
100
200
300
400
500
600
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Wnt signaling pathwayKEGGko04310
Wnt signaling pathwayKEGGhsa04310

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164712563BisphosphonatesChemicalClinicalAnnotationassociatedPD
PA445187OsteonecrosisDiseaseClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
384098372024SFRP5 Partially Inhibits the Proliferation and Migration of Airway Smooth Muscle Cells in Children with Asthma by Regulating the Wnt/β-Catenin Signaling Pathway.0
387143252024Secreted frizzled-related protein 5 overexpression reverses oxLDL-induced lipid accumulation in human vascular smooth muscle cells.0
384098372024SFRP5 Partially Inhibits the Proliferation and Migration of Airway Smooth Muscle Cells in Children with Asthma by Regulating the Wnt/β-Catenin Signaling Pathway.0
387143252024Secreted frizzled-related protein 5 overexpression reverses oxLDL-induced lipid accumulation in human vascular smooth muscle cells.0
366311992023Frizzled receptors and SFRP5 in lipid metabolism: Current findings and potential applications.1
371919682023TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis.0
366311992023Frizzled receptors and SFRP5 in lipid metabolism: Current findings and potential applications.1
371919682023TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis.0
343822032022Elevated Serum SFRP5 Levels During Preeclampsia and Its Potential Association with Trophoblast Dysfunction via Wnt/β-Catenin Suppression.6
347799872022The role of Wnt pathway antagonists in early-stage lung adenocarcinoma.3
354002412022Circulating level of serum secreted frizzled-related protein 5 decreases in polycystic ovary syndrome.0
360772702022Increased Secreted Frizzled-Related Protein 5 mRNA Expression in the Adipose Tissue of Women with Nonalcoholic Fatty Liver Disease Associated with Obesity.0
343822032022Elevated Serum SFRP5 Levels During Preeclampsia and Its Potential Association with Trophoblast Dysfunction via Wnt/β-Catenin Suppression.6
347799872022The role of Wnt pathway antagonists in early-stage lung adenocarcinoma.3
354002412022Circulating level of serum secreted frizzled-related protein 5 decreases in polycystic ovary syndrome.0

Citation

Dessen P

SFRP5 (secreted frizzled related protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/42278/sfrp5-(secreted-frizzled-related-protein-5)